Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction: Obstructive sleep apnea (OSA) is increasingly recognized as an important metabolic risk factor due to recurrent episodes of intermittent hypoxia (IH). Clinical studies have linked OSA with...
Introduction: Altered gut motility is increasingly recognized as a contributor to metabolic dysfunction through the gut–brain axis. Enterosynes are gut-derived bioactive molecules that regulate intestinal motility and influence...
Introduction: The gut microbiome and obesity are both known to influence cancer immunotherapy outcomes, yet the interaction between diet, obesity, and the microbiome has remained unclear. This landmark...
Introduction: Intrahepatic cholangiocarcinoma (ICC) is an aggressive primary liver cancer with poor prognosis and limited treatment options. While ICC has traditionally been considered a malignancy of biliary epithelial...
Introduction: Liver fibrosis is the key determinant of long-term outcomes in metabolic dysfunction-associated steatohepatitis (MASH). Activated hepatic stellate cells (HSCs) drive fibrogenesis, but effective antifibrotic therapies remain unavailable....
Introduction: The progression from metabolic dysfunction-associated fatty liver (MAFL) to metabolic dysfunction-associated steatohepatitis (MASH) is driven by complex interactions between hepatocytes and immune cells. This study identifies a...
Introduction: Cardiovascular–Kidney–Metabolic (CKM) syndrome recognizes the close interaction between obesity, type 2 diabetes, chronic kidney disease, and cardiovascular disease. This review highlights the emerging role of the gut...
Small intestinal adenocarcinoma (SIA) is a rare gastrointestinal cancer with limited disease-specific prognostic biomarkers and generally poor outcomes. This nationwide Dutch population-based study evaluated whether three routinely available...
Introduction: Metabolic dysfunction–associated steatotic liver disease (MASLD) is closely linked to insulin resistance and type 2 diabetes, with the liver traditionally viewed as a key regulator of blood...
Introduction: Pancreatic ductal adenocarcinoma (PDAC) develops through a series of precursor lesions, beginning with acinar-to-ductal metaplasia (ADM) and progressing to pancreatic intraepithelial neoplasia and invasive cancer. While genetic...
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