Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Sarcopenia and frailty are both clinical conditions that can significantly influence the progression and outcomes of liver diseases, including decompensated cirrhosis. Below is a detailed explanation of each...
Type-1, Type-2, and Type-3 inflammation are classifications of immune responses that represent distinct biological pathways activated in response to different types of stimuli. These inflammation types play critical...
Systemic Inflammatory Index (SII): The Systemic Inflammatory Index (SII) is a biomarker that reflects systemic inflammation by combining platelet, neutrophil, and lymphocyte counts into a single formula. It...
The efficacy of TDF, TAF, TMF, and the TDF-to-TAF switch in treating chronic hepatitis B (CHB) has been extensively studied to identify the most effective regimen for individualized...
The gut mycobiome refers to the fungal community residing within the human gastrointestinal system. While the gut microbiome (bacteria) has been extensively studied, the mycobiome remains underexplored, despite...
The direct bilirubin-to-albumin ratio (DBAR) has emerged as a reliable prognostic marker for assessing 28-day mortality in critically ill patients with cirrhosis, as demonstrated by a study utilizing...
Immune dysfunction and infection risk are critical and interlinked concerns in patients with advanced liver disease, including cirrhosis and acute-on-chronic liver failure (ACLF). The immune system undergoes profound...
Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease characterized by progressive destruction of bile ducts, leading to cholestasis and liver damage. Ursodeoxycholic acid (UDCA) is the...
Bezafibrate has emerged as a significant therapeutic agent for improving transplant-free survival in patients with primary biliary cholangitis (PBC) when used in combination with ursodeoxycholic acid (UDCA). PBC...
The FITCH trial investigated the efficacy of bezafibrate, a broad peroxisome proliferator-activated receptor (PPAR) agonist, in alleviating moderate to severe pruritus in patients with fibrosing cholangiopathies, including primary...
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