Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Integrated single-cell and single-nucleus RNA sequencing identified a distinct hepatic stellate cell population associated with MASH-related fibrosis. AREL1 emerged as a characteristic gene of this fibrogenic stellate-cell population...
This review proposes a processing-centred gut–liver–brain axis, positioning MASLD as a metabolic amplifier between ultra-processed food exposure and cognitive decline. Ultra-processed foods are not simply high in sugar,...
Introduction: Metabolic dysfunction–associated steatotic liver disease (MASLD) has emerged as one of the most prevalent chronic liver diseases worldwide, affecting nearly one-third of adults and a majority of...
Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is traditionally linked to obesity, but an increasing number of patients develop significant hepatic steatosis despite having a normal body mass...
Resmetirom is the first FDA-approved therapy for patients with MASH/MASLD and stage F2–F3 fibrosis, creating an urgent need for reliable noninvasive methods to identify treatment candidates. This study...
Introduction: Obesity is a major risk factor for several malignancies, including colorectal, pancreatic, liver, endometrial, and other obesity-associated cancers (OACs). With the growing global burden of obesity, glucagon-like...
Introduction: Metabolic Dysfunction-Associated Steatotic Liver Disease, Alcohol-Associated Liver Disease, and the recently recognized MetALD phenotype represent a rapidly expanding spectrum of chronic liver disease with overlapping metabolic and...
Introduction Chronic Liver Disease continues to rise globally, driven predominantly by Metabolic Dysfunction-Associated Steatotic Liver Disease and alcohol-associated liver disease. Accurate evaluation of fibrosis severity and hepatic functional...
Introduction Metabolic Dysfunction-Associated Steatotic Liver Disease is increasingly recognized as a systemic disorder extending beyond hepatic steatosis and fibrosis. Cardiovascular disease remains the leading cause of mortality in...
Introduction Metabolic Dysfunction-Associated Steatotic Liver Disease is increasingly recognized as a major driver of progressive liver fibrosis, cirrhosis and liver-related mortality worldwide. Although obesity, insulin resistance and diabetes...
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