Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction Hepatocellular carcinoma with portal vein tumor thrombus represents one of the most aggressive forms of liver cancer, associated with poor prognosis and limited survival. Standard treatment relies...
Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is now the leading cause of chronic liver disease worldwide and closely parallels the epidemics of obesity and type 2 diabetes....
Introduction Hepatocellular carcinoma remains a major global cancer burden, with high recurrence rates even after curative therapies such as resection or ablation. Historically, effective adjuvant treatments have been...
Introduction Hepatocellular carcinoma (HCC) outcomes are critically dependent on stage at diagnosis, with early-stage disease offering opportunities for curative therapies such as resection, ablation, or transplantation. Despite advances...
Introduction Fibrolamellar carcinoma (FLC) is a rare and biologically distinct primary liver cancer that predominantly affects adolescents and young adults without cirrhosis or other chronic liver disease. Unlike...
Introduction Transarterial chemoembolization (TACE) remains one of the most important treatments for unresectable hepatocellular carcinoma, but its clinical benefit is often limited by post-procedural liver injury. Traditionally, this...
Introduction The Barcelona Clinic Liver Cancer (BCLC) classification has remained the cornerstone for staging, prognosis, and treatment allocation in hepatocellular carcinoma for more than two decades. Its strength...
Recurrence of hepatocellular carcinoma (HCC) after liver transplantation occurs in 15–20% of patients and remains a major determinant of post-transplant survival. This international matched cohort study evaluated whether...
Introduction: The Biomarkers Used for HCC Surveillance Ultrasound (US) is the backbone of hepatocellular carcinoma (HCC) surveillance, but its sensitivity for early-stage HCC is imperfect. Blood-based biomarkers are...
Introduction Alpha-fetoprotein (AFP) remains the most widely used biomarker in hepatocellular carcinoma (HCC) surveillance. Although AFP alone is insufficient for screening, its combination with ultrasound improves early HCC...
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