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Trending Topics in Gastroenterology

Explore current gastroenterology questions, clinical answers, and emerging research by topic.

21

Prognostic value of LSM in PBC- AJG Feb.26

Risk stratification in primary biliary cholangitis (PBC) traditionally relies on biochemical response to ursodeoxycholic acid, but liver stiffness measurement (LSM) is increasingly used to assess fibrosis and portal...

22

How Alcohol Acts as a ‘Second Hit’ in HBV-Driven Liver Cancer- AJG Feb.26

Introduction Hepatocellular carcinoma (HCC) commonly arises from chronic liver injury due to hepatitis B virus (HBV), alcohol use, metabolic dysfunction, or combinations of these factors. While each risk...

23

EUS-guided liver biopsy – a novel technique (GIE, Jan-2026)

Indications of EUS-Guided Liver Biopsy EUS-guided liver biopsy (EUS-LB) is increasingly utilized as a minimally invasive technique for obtaining liver tissue samples. Common indications for EUS-LB include: Evaluation...

24

HBV Genotype and Biomarkers Predict Severe Flares After NA Cessation

The study highlights the significant role of HBV genotype and end-of-treatment (EOT) biomarkers in predicting severe virologic relapses (SVRel) and severe biochemical flares (SBF) after nucleos(t)ide analogue (NA)...

25

The hepatitis B vaccine—the first anti-cancer vaccine (Lancet Gastro Hepato 2026)

The hepatitis B vaccine, often hailed as the first anti-cancer vaccine, represents a groundbreaking achievement in global public health. Chronic hepatitis B virus (HBV) infection is a leading...

26

Rat Hepatitis E - J of Hepatology-Jan.26

Rat Hepatitis E (rHEV), also known as Rocahepevirus ratti, is an emerging zoonotic pathogen that has garnered significant attention in recent years due to its potential to infect...

27

HBsAg, HBeAg and HCC prediction

HBsAg (Hepatitis B surface antigen) and HBeAg (Hepatitis B e antigen) are important biomarkers in understanding the progression and risk factors of chronic hepatitis B virus (HBV) infection,...

28

Large-Scale Profiling of HBsAg Levels in Chronic Hepatitis B for Functional Cure Development

The large-scale profiling of hepatitis B surface antigen (HBsAg) levels in patients with chronic hepatitis B (CHB) is a critical area of research aimed at advancing the development...

29

STASH Trial

The STASH trial (Short for "Steroid Tapering in Severe Alcohol-associated Hepatitis") was a multicenter, open-label randomized clinical trial aimed at evaluating the efficacy and safety of a tapered...

30

Zetomipzomib and the PORTOLA Trial

Zetomipzomib and the PORTOLA Trial represent a significant advancement in the treatment of autoimmune hepatitis (AIH), particularly for patients who are inadequately controlled on standard therapies like steroids...

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