Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction: Introduction: Liver transplantation increasingly relies on extended-criteria donor (ECD) and donation-after-circulatory-death (DCD) grafts to address organ shortages. However, these grafts are more susceptible to ischemia-reperfusion injury, which...
Introduction Alcohol-Associated Liver Disease has become one of the leading indications for Liver Transplantation worldwide. Although transplantation provides excellent survival benefit, post-transplant alcohol relapse remains a major concern...
Acute-on-chronic liver failure (ACLF) is a severe syndrome characterized by acute decompensation, organ failure, and high short-term mortality in patients with cirrhosis. However, ACLF lacks a universally accepted...
Introduction Ischemia–reperfusion injury (IRI) remains a major barrier in organ transplantation and contributes significantly to graft dysfunction, early allograft injury and organ discard. Ferroptosis, an iron-dependent form of...
Introduction Colorectal liver metastases remain a major cause of cancer-related mortality, and curative treatment is traditionally limited to patients eligible for hepatic resection. However, many patients present with...
Introduction Liver transplantation is the definitive treatment for children with end-stage liver disease, yet waitlist mortality remains a major challenge, particularly in infants and critically ill children with...
Introduction Kidney and liver transplantation substantially improve survival and quality of life in patients with end-stage organ disease. However, cardiovascular disease (CVD) remains a leading cause of long-term...
Introduction Biliary cast syndrome (BCS) is an uncommon but clinically significant biliary complication after liver transplantation, characterized by the formation of obstructive biliary debris within the graft biliary...
Introduction Liver transplantation has dramatically improved survival in patients with end-stage liver disease and hepatocellular carcinoma. However, long-term outcomes are often compromised by complications such as graft rejection,...
Introduction Donation after circulatory death (DCD) has emerged as an important strategy to expand the donor pool in liver transplantation. However, compared to brain-dead donors, DCD grafts are...
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