Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Intratumoral heterogeneity (ITH) plays a critical role in immunotherapy resistance, significantly influencing the success or failure of immune checkpoint inhibitor therapies. ITH refers to the genetic, epigenetic, and...
Surveillance for esophageal cancer, particularly in the context of patients treated with neoadjuvant chemoradiotherapy (nCRT), is a critical area of research and clinical practice. Active surveillance is an...
Explanation of Key Terms: Microsatellite-Stable (MSS) Colorectal Cancer (CRC): Microsatellite stability refers to the genetic stability of certain DNA sequences called microsatellites, which are short, repetitive sequences scattered...
The immunogenomics of cholangiocarcinoma (CCA) is a rapidly evolving field that explores the interplay between genetic and non-genetic alterations in tumor cells and immune cells, and their impact...
The LEAP-014 trial investigated the efficacy of adding lenvatinib to pembrolizumab and chemotherapy in patients with metastatic esophageal squamous cell carcinoma (ESCC). Unfortunately, the results were disappointing, as...
Oncology and Molecular Medicine is a highly specialized and interdisciplinary field of science and medicine that focuses on understanding, diagnosing, and treating cancer at the molecular and cellular...
Non-Coding RNA (ncRNA) refers to RNA molecules that are transcribed from DNA but do not encode proteins. Unlike messenger RNA (mRNA), which serves as a template for protein...
--- Definition: Oncogenes are mutated or abnormally expressed versions of normal cellular genes known as proto-oncogenes. Proto-oncogenes encode proteins that regulate essential cellular processes such as growth, proliferation,...
Microvascular invasion (MVI) is a critical pathological feature in hepatocellular carcinoma (HCC) that significantly influences prognosis and postoperative recurrence patterns, particularly aggressive recurrence, following hepatectomy. Here's a detailed...
Hepatocellular adenoma (HCA) and focal nodular hyperplasia (FNH) are two types of benign liver lesions that can sometimes be difficult to differentiate based on imaging studies due to...
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