Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction Gastric polyps are frequently encountered during upper gastrointestinal endoscopy and represent a heterogeneous group of lesions ranging from benign fundic gland polyps to premalignant adenomas and neuroendocrine...
Introduction Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disease characterized by progressive esophageal inflammation that can evolve into fibrostenotic complications such as strictures and food impaction. Endoscopy plays...
Introduction Eosinophilic esophagitis (EoE) is a chronic immune-mediated oesophagal disease in children that causes feeding difficulty, vomiting, abdominal pain, dysphagia, and poor quality of life. Standard therapy often...
What Are MEK Inhibitors? MEK inhibitors are targeted drugs that block the MAPK/ERK signalling pathway, specifically the MEK (mitogen-activated protein kinase kinase) enzyme. This pathway regulates cell proliferation,...
Introduction Eosinophilic gastrointestinal diseases (EGIDs) are chronic, immune-mediated disorders defined by eosinophil-predominant inflammation in the GI tract. Over the past 30 years, EGIDs—especially eosinophilic esophagitis (EoE)—have risen sharply...
Introduction Iron deficiency anaemia (IDA) has long been considered an important red flag for underlying gastrointestinal (GI) malignancy. However, with evolving referral patterns, widespread endoscopic access, and prior...
Many patients continue to experience nocturnal heartburn or regurgitation despite taking a standard morning proton pump inhibitor (PPI). Current practice often escalates to a second (evening) PPI dose,...
This large, single-center, prospective cohort study evaluated a non-endoscopic capsule sponge (CS) triage pathway for patients routinely referred with reflux symptoms over 4 years. The goal was to...
Gastroparesis is a chronic, debilitating disorder characterised by nausea, vomiting, early satiety, postprandial fullness, and abdominal pain. Current pharmacologic options are limited by modest efficacy and safety concerns,...
Introduction “Laryngopharyngeal reflux (LPR)” has become a catch-all label for chronic throat and upper airway complaints—cough, throat clearing, hoarseness, phlegm, throat pain—often without objective evidence of reflux. This...
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