Colon Capsule Endoscopy vs Conventional Colonoscopy After Diverticulitis- Endoscopy | March 2026. DOI: 10.1055/a-2695-6904

Introduction

After CT-confirmed diverticulitis, follow-up colonoscopy is routinely performed to exclude malignancy. Colon capsule endoscopy (CCE) offers a non-invasive alternative, but its impact on patient experience remains unclear.

Summary

In this randomized controlled trial of 159 patients, CCE was compared with colonoscopy 4–6 weeks after diverticulitis. Patients expected colonoscopy to cause greater discomfort; however, experienced physical and mental discomfort did not differ significantly between groups. Examination completion was slightly higher with colonoscopy (92%) than CCE (84%). No malignancies were detected. Nearly half of patients preferred CCE for future evaluation. The study shows that CCE is safe and patient-preferred, though colonoscopy remains diagnostically more complete.