Endoscopy

Clinical knowledge base written and curated by GastroAGI Team from primary medical literatureLast updated August 1, 2026

Overview

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Saline-Immersion ESD with Dynamic Traction for Complex Ileocecal Valve Adenomas: GIE | August 2026

Introduction: Endoscopic submucosal dissection (ESD) of lesions involving the ileocecal valve (ICV) and extending into the terminal ileum is among the most technically challenging colorectal procedures. Difficult scope stability, abundant submucosal fat, and limited visualization...

Paclitaxel-Coated Balloon Dilator for Recurrent Oesophagal Strictures: GIE | May 2026

Introduction: Recurrent esophageal strictures remain a frustrating clinical problem, often requiring repeated endoscopic dilations with persistent dysphagia and reduced quality of life. Although conventional balloon dilation effectively relieves obstruction, it does not prevent restricture formation....

Cryoballoon Ablation: GIE | July 2026

Introduction: Cryoballoon ablation (CbA) is an emerging endoscopic ablative technology that delivers focal cryotherapy without the need for a decompression tube, making the procedure simpler and more efficient than traditional cryospray systems. Initially developed for...

Does Earlier Endoscopy Improve Outcomes in Oesophageal Food Bolus Impaction?: Gut | July 2026

Introduction: European Society of Gastrointestinal Endoscopy (ESGE) guidelines recommend emergent endoscopy within 6 hours for complete oesophageal food bolus obstruction and urgent endoscopy within 24 hours for incomplete obstruction. However, these recommendations are largely based...

Excellent Bowel Preparation Improves Detection of Serrated Polyps During FIT-Based Colonoscopy: GIE | July 2026

Introduction: Serrated polyps, particularly proximal sessile serrated lesions (SSLs), are increasingly recognised as major precursors of post-colonoscopy colorectal cancer (PCCRC). This study evaluated whether achieving excellent bowel preparation (Boston Bowel Preparation Scale [BBPS] 8–9) provides...

Generative Chromoendoscopy for Detecting Early Gastric Neoplasms: Endoscopy | July 2026

Introduction: Conventional chromoendoscopy enhances the detection of early gastric neoplasms but requires dye spraying, adding time and procedural complexity. This proof-of-concept multicenter study evaluated Generative Chromoendoscopy, an artificial intelligence–based technique that uses deep learning to...

G-POEM for Refractory Gastroparesis and role of EndoFLIP to Predict Clinical Success: GIE| July 2026

Introduction: Gastric peroral endoscopic myotomy (G-POEM) has become an effective treatment for refractory gastroparesis. Endoscopic Functional Luminal Imaging Probe (EndoFLIP) allows real-time assessment of pyloric physiology, but its ability to predict clinical response remains uncertain....

Randomized Comparison of Endoscopic Gastroplasty Techniques for Obesity: Clinical Gastrointestinal Endoscopy | July 2026

Introduction: Endoscopic gastroplasty has emerged as an effective minimally invasive treatment for obesity, offering an alternative to bariatric surgery. Multiple endoscopic techniques are currently available, but comparative evidence has been limited. This randomized pragmatic trial...

Low-Volume PEG for Inpatient Colonoscopy: Annals of Internal Medicine | July 2026

Introduction: Adequate bowel preparation is often difficult to achieve in hospitalized patients because of advanced age, comorbidities, immobility, and concurrent medications. This multicenter randomized INTERPRET trial compared 1-L, 2-L, and 4-L polyethylene glycol (PEG) regimens...

Computer-Aided Detection (CADe) in Routine Colonoscopy: Gastroenterology | July 2026

Introduction: Adenoma detection rate (ADR) is the most important quality indicator for colonoscopy and is directly associated with reduced colorectal cancer risk. Although randomized trials have shown that artificial intelligence–based computer-aided detection (CADe) improves ADR,...

Cold vs Hot Snare Polypectomy for Pedunculated Colorectal Polyps: Endoscopy | July 2026

A randomized controlled trial published in Endoscopy (July 2026) compared cold snare polypectomy (CSP) with hot snare polypectomy (HSP) for small pedunculated colorectal polyps. Key findings CSP eliminated delayed post-polypectomy bleeding (DPPB) and was significantly...

Novel Catheter Improves Endoscopic Transpapillary Gallbladder Drainage in Malignant Biliary Stricture VideoGIE | July 2026

Introduction: Acute cholecystitis in patients with malignant biliary obstruction can be difficult to manage, particularly when surgery is not feasible. Endoscopic transpapillary gallbladder drainage (ETGBD) is an attractive minimally invasive option, but selective cannulation of...

AI for Early Esophageal Cancer Detection: AJG | July 2026

Introduction: Early detection of esophageal squamous cell carcinoma (ESCC) is critical for curative endoscopic treatment. However, subtle lesions are often missed during routine endoscopy. This meta-analysis evaluated whether deep learning (AI)-based endoscopic systems can improve...

EndoBarrier Improves Diabetes and Weight Loss: Ann Surg | July 2026

Introduction: Endoscopic metabolic therapies have emerged as less invasive alternatives to bariatric surgery for patients with obesity and poorly controlled type 2 diabetes mellitus (T2DM). The EndoBarrier duodenal-jejunal bypass liner (DJBL) is an endoscopically placed...

Immediate Endoscopic Necrosectomy in Necrotizing Pancreatitis: Gastroenterology | July 2026

Introduction: Endoscopic ultrasound (EUS)-guided transmural drainage is the standard minimally invasive treatment for symptomatic necrotizing pancreatitis. However, the optimal timing of direct endoscopic necrosectomy (DEN) following drainage remains uncertain. While the conventional step-up approach reserves...

Endoscopy After Bevacizumab Appears Safe: GIE | July 2026

Introduction: Bevacizumab is widely used in metastatic colorectal cancer (mCRC) because of its survival benefits but is associated with impaired wound healing, gastrointestinal perforation, and bleeding. These concerns often lead clinicians to delay endoscopic procedures...

Colorectal ESD Perforation: Endoscopy | July 2026

Introduction: Endoscopic submucosal dissection (ESD) enables en bloc resection of large colorectal neoplasms with excellent oncological outcomes. However, concerns about perforation have limited its widespread adoption. This large prospective multicenter study evaluated the incidence, risk...

Duodenal Mucosal Resurfacing REMAIN-1 Study: DDW | 2026

Introduction: Obesity has become one of the greatest global health challenges. New incretin-based therapies—including semaglutide, tirzepatide, resmetirom, and SGLT2 inhibitors such as empagliflozin—have transformed the treatment of obesity, diabetes, and MASLD. However, many patients discontinue...

EUS-FNAB for Solid Pancreatic Lesions: GIE | July 2026

Introduction: Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is the standard technique for diagnosing solid pancreatic lesions. Traditionally, biopsy specimens are processed for cytology, often requiring on-site cytopathology support. This multicenter prospective study evaluated whether directly placing...

Durable Endoscopic Partial Reversal of Roux-en-Y Gastric Bypass Using Parallel LAMS Septotomy: GIE | July 2026

Introduction: Although Roux-en-Y gastric bypass (RYGB) is an effective bariatric procedure, a small proportion of patients develop severe nutritional complications, refractory dumping syndrome, or other debilitating adverse events requiring reversal. This study describes a novel...

EUS Double Drainage for Malignant Dual Obstruction : Gut | Jul 2026

Introduction: Simultaneous malignant distal biliary obstruction (MDBO) and gastric outlet obstruction (GOO), commonly caused by advanced pancreatic, biliary, or duodenal cancers, presents a major palliative challenge. Conventional endoscopic approaches often require repeated interventions and may...

Endoscopic Mucosal and Submucosal Cutting in benign esophageal stricture: Gut | July 2026

Introduction: Long benign esophageal strictures remain one of the most difficult benign conditions to manage. Although endoscopic dilation and incision techniques provide temporary relief, recurrence is common, often requiring repeated interventions. This study introduces a...

Economic Impact of POEM and ESD: GIE | June 2026

Introduction: Peroral endoscopic myotomy (POEM) and endoscopic submucosal dissection (ESD) have revolutionized the management of esophageal motility disorders and early gastrointestinal neoplasia. Despite their proven clinical benefits, widespread adoption has been limited by concerns regarding...

Remimazolam Improves Sedation Safety During ERCP : GIE | Jun 2026

Introduction: Deep sedation is essential for successful endoscopic retrograde cholangiopancreatography (ERCP), a technically complex procedure frequently performed in elderly patients and those with significant comorbidities. Propofol remains the most commonly used sedative agent because of...

Sustainability Cuts Endoscopy Carbon Footprint and Costs : GIE | Jun 2026

Introduction: Endoscopy services generate substantial amounts of healthcare waste due to high procedural volumes, extensive use of disposable accessories, and stringent infection-control requirements. As healthcare systems increasingly focus on environmental sustainability, reducing the ecological impact...

Modern Endoscopic Management of Flat Colonic Neoplasia : Endoscopy | June 2026

Introduction: Non-pedunculated colonic neoplasia (NPCN), including flat and sessile colorectal lesions, is being detected with increasing frequency due to widespread colorectal cancer screening and advances in high-definition endoscopy. Compared with pedunculated polyps, these lesions present...

EUS-GJ Preferred for Malignant Gastric Outlet Obstruction : GIE | Feb 2026

Introduction: Malignant gastric outlet obstruction (GOO) is a debilitating complication of advanced gastrointestinal and pancreatobiliary cancers, leading to nausea, vomiting, poor oral intake, malnutrition, and impaired quality of life. Palliation aims to restore enteral intake...

Structured Closure Improves Safety of Duodenal ESD and EFTR : GIE | April 2026

Introduction: Endoscopic submucosal dissection (ESD) and endoscopic full-thickness resection (EFTR) have expanded the therapeutic options for duodenal epithelial and sub epithelial lesions, allowing organ-preserving treatment of lesions that previously required surgery. However, the duodenum remains...

Bariatric Endoscopy in the GLP-1 Era : Frontline Gastroenterol | June 2026

Introduction: Introduction: Obesity affects more than one billion individuals globally and is a major driver of type 2 diabetes, cardiovascular disease, metabolic dysfunction–associated steatotic liver disease (MASLD), and multiple obesity-related cancers. While incretin-based therapies such...

Advanced Endoscopy Enhances Celiac Atrophy Detection : GIE | May 2026

Introduction Celiac Disease remains dependent on histological confirmation of villous atrophy for diagnosis. However, endoscopic recognition of subtle mucosal abnormalities has become increasingly important for improving biopsy targeting and reducing missed disease. Problem Statement Conventional...

Water-Assisted Colonoscopy: Endoscopy| May 2026

Water-assisted colonoscopy (WAC), also known as hydrocolonoscopy, is an evolving insertion technique in which water is used instead of, or alongside, gas insufflation during colonoscope advancement. Over recent years, growing evidence has shown that WAC...

Optimizing Barrett’s Endoscopy Quality to Reduce Missed Neoplasia : FG | May 2026

Introduction Barrett's Esophagus is the principal precursor lesion for Esophageal Adenocarcinoma. Surveillance endoscopy aims to detect dysplasia and early neoplasia at a curable stage; however, post-endoscopy upper gastrointestinal cancers remain a significant problem. Contemporary UK...

Recurrent Colorectal Polyps Require Advanced, Structured Endoscopic Management : Frontline Gastroenterology | May 2026

Introduction Colorectal Polyps are identified in up to half of screening colonoscopies and represent key precursor lesions for Colorectal Cancer. Advances in endoscopic resection techniques have dramatically reduced the need for surgery; however, recurrence or...

Recurrent Colorectal Polyps Require Advanced, Structured Endoscopic Management : Frontline Gastroenterology | May 2026

STER Demonstrates Strong Real-World Outcomes for Upper GI Subepithelial Tumors : Gastrointest Endosc | May 2026

Introduction Submucosal Tunneling Endoscopic Resection has emerged as an important minimally invasive approach for management of upper gastrointestinal Subepithelial Tumors arising from or closely associated with the muscularis propria layer. Although extensive Asian experience has...

Diathermy Principles Every Endoscopist Should Understand ; Frontline Gastroenterol | May 2026

Introduction Electrosurgery forms the foundation of modern therapeutic gastrointestinal endoscopy. Procedures including polypectomy, Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection, endoscopic sphincterotomy and third-space endoscopy all rely on controlled delivery of electrical energy to tissue. Despite...

Sedation Strategy Influences Aspiration Risk After PEG : Frontline Gastroenterol | May 2026

Introduction Percutaneous Endoscopic Gastrostomy is widely performed for long-term enteral nutritional support in patients with neurological disease, dysphagia and chronic debilitating illness. Aspiration pneumonia remains one of the most important early complications following PEG insertion...

3D-Printed Distal Caps for ESD: Clinical and Translational Gastroenterology | May 2026

Conventional Method Commercial distal attachment caps are routinely used during Endoscopic Submucosal Dissection to improve visualization, tissue traction, and procedural stability. Although effective, these caps are commercially manufactured, relatively costly, and offer limited customization for...

Post-ERCP Bleeding Risks Clarified in Large Meta-analysis : Gastrointest Endosc | May 2026

Introduction Endoscopic retrograde cholangiopancreatography (ERCP) is a cornerstone therapeutic procedure in pancreatobiliary disease but carries a risk of clinically significant bleeding, particularly following therapeutic interventions such as sphincterotomy. Accurate identification of bleeding predictors is essential...

Predictors of Post-ERCP Bleeding Identified in Large Meta-analysis : Gastrointest Endosc | May 2026

Introduction Endoscopic retrograde cholangiopancreatography (ERCP) is an essential therapeutic procedure in pancreatobiliary disease but remains associated with important adverse events, including postprocedural bleeding. Although bleeding occurs relatively infrequently, it can result in significant morbidity, need...

International Consensus Defines Best Practices for EUS-Guided Gastroenterostomy : Gastrointestinal Endoscopy | May 2026

Introduction Endoscopic ultrasound–guided gastroenterostomy (EUS-GE) has rapidly emerged as an important minimally invasive option for the management of gastric outlet obstruction, offering an alternative to surgical bypass and enteral stenting. As adoption increases globally, EUS-GE...

EUS-Directed Transenteric ERCP Expands Options in Surgically Altered Anatomy : Gastrointestinal Endoscopy | May 2026

Introduction Biliary intervention in patients with surgically altered anatomy remains one of the most technically challenging areas in therapeutic endoscopy. Conventional enteroscopy-assisted ERCP is often limited by difficult limb access, prolonged procedure time and reduced...

Same-Day Discharge After G-POEM Appears Safe in Selected Patients | Gastrointestinal Endoscopy

Introduction Gastric per oral endoscopic myotomy (G-POEM) has emerged as an effective minimally invasive therapy for refractory gastroparesis. However, post-procedural care remains variable across centers, with no clear consensus on whether patients require routine overnight...

Digital Family History Assessment Improves CRC Risk Stratification in Endoscopy | Endoscopy

Introduction Family history remains a critical but underused tool in colorectal cancer (CRC) risk assessment. Despite its importance in identifying individuals at increased hereditary risk, family history is often incompletely captured in routine endoscopy practice,...

Single-Dose NSAIDs in ERCP: Gastroenterology | May 2026

Introduction Post-ERCP pancreatitis (PEP) remains one of the most common and serious complications of Endoscopic Retrograde Cholangiopancreatography. Rectal NSAIDs such as Indomethacin and Diclofenac are strongly recommended for PEP prevention. However, concerns about renal safety—especially...

OTSC vs Band Ligation in Diverticular Bleeding: GIE | April 2026

Introduction Colonic diverticular bleeding is an increasingly common cause of lower gastrointestinal bleeding, particularly with aging populations. Although many cases resolve spontaneously, recurrent or severe bleeding often requires endoscopic intervention. Techniques such as endoscopic band...

GLP-1 Therapy vs Bariatric Endoscopy: Obesity Surgery | April 2026

Introduction The management of obesity and type 2 diabetes has rapidly evolved, with GLP-1 receptor agonists emerging as highly effective pharmacological options, while bariatric endoscopic therapies provide minimally invasive procedural alternatives. Traditionally, metabolic bariatric surgery...

Should We Continue Colonoscopy surveillance After 75?: JAMA | April 2026

Introduction Colorectal cancer (CRC) screening and surveillance have significantly reduced cancer-related mortality. However, in adults aged ≥75 years, clinical decision-making becomes complex. While cancer risk increases with age, competing risks—particularly non-cancer mortality and frailty—also rise...

BSG Interim Position on LAMS Use After AXIOS Recall: FG | April 2026

Introduction Lumen-apposing metal stents (LAMS) have become central to therapeutic endoscopic ultrasound (T-EUS), especially for pancreatic fluid collection drainage, EUS-guided gallbladder drainage, choledochoduodenostomy, gastrojejunostomy, and EDGE procedures. In December 2025, the urgent recall of selected...

AI in Colonoscopy Withdrawal Time Accuracy: Endoscopy | April 2026

Introduction Withdrawal time during colonoscopy is a key quality indicator directly linked to adenoma detection and colorectal cancer prevention. However, accurate measurement in routine practice is often inconsistent, especially during procedures involving interventions. This variability...

GLP-1 Agonists Before Endoscopy (OCULUS Trial): JAMA | April 2026

Introduction Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) agonists have rapidly become integral in the management of type 2 diabetes, obesity, and metabolic diseases due to their effects on glycemic control and weight loss....

NBI and Acetic Acid Chromoendoscopy in Barrett’s Oesophagus: BMJ Open Gastroenterology | March 2026

Introduction Barrett’s oesophagus represents a well-established precursor to oesophageal adenocarcinoma, with progression from intestinal metaplasia to dysplasia and invasive cancer. Given the poor prognosis of advanced disease, early detection through surveillance endoscopy remains critical. Conventional...

Choosing the Right Snare in Gastrointestinal Endoscopy

Introduction Endoscopic resection has evolved rapidly, with increasing emphasis on precision, safety, and complete lesion removal. While advances in techniques such as EMR and ESD have transformed outcomes, one fundamental aspect—snare selection—remains underappreciated. The physical...

Routine Esophagram After POEM: Clinical Insight | Inspired by Expert Commentary

Introduction Routine esophagram after POEM has long been considered a safety checkpoint to rule out leaks before resuming oral intake. However, with improved procedural techniques and safety, its real-world value is increasingly being questioned. Clinical...

Post-Banding Ulcer Bleeding: Alime Pharmaco & Therap | March 2026

Introduction Endoscopic band ligation (EBL) remains the standard of care for managing oesophagal varices, both in acute variceal bleeding and for prophylaxis. However, post-banding ulcer bleeding (PBUB) is an important and often under-recognised complication, associated...

Endoscopic Palliation in Pancreatic Cancer: AMJ, March 2026

This article reviews the endoscopic approach to palliation in pancreatic cancer, emphasising that most patients present with unresectable or metastatic disease, so symptom control becomes central to care. Because of the pancreas’ location, tumour growth...

G-POEM in Severe Refractory Gastroparesis: Gut March 2026

Introduction Gastroparesis is a chronic disorder characterised by delayed gastric emptying without mechanical obstruction, leading to symptoms such as nausea, vomiting, early satiety, bloating, and postprandial fullness. Treatment options for severe and refractory gastroparesis are...

Colon Capsule Endoscopy vs Conventional Colonoscopy After Diverticulitis- Endoscopy | March 2026. DOI: 10.1055/a-2695-6904

Introduction After CT-confirmed diverticulitis, follow-up colonoscopy is routinely performed to exclude malignancy. Colon capsule endoscopy (CCE) offers a non-invasive alternative, but its impact on patient experience remains unclear. Summary In this randomized controlled trial of...

METARSI Trial: Endoscopy International Open, Feb.26

The METARSI trial is a prospective, multicenter randomised controlled study comparing partially covered self-expanding metal stents (PC-SEMS) versus uncovered SEMS (U-SEMS) in patients with malignant unresectable distal biliary obstruction (DBO) undergoing ERCP. A total of...

EUS-Directed Transgastric ERCP (EDGE) in RYGB: GIE, Feb.26

Endoscopic ultrasound–directed transgastric ERCP (EDGE) has emerged as a transformative technique for managing biliary and pancreatic diseases in patients with Roux-en-Y gastric bypass (RYGB) anatomy. Traditional ERCP is technically challenging in RYGB due to altered...

Linaclotide Administration plus PEG for Colonoscopy Bowel Preparation- AJG Feb.26

High-volume polyethene glycol (PEG) solutions remain a major barrier to successful colonoscopy bowel preparation because of poor tolerability. Linaclotide, a guanylate cyclase-C agonist that increases intestinal secretion and transit, has been explored as an adjunct...

SOCCER Trial: Forceps Boost Cannulation Success in Difficult ERCP- AJG Feb.26

Introduction Difficult biliary cannulation remains one of the most common and consequential problems in ERCP. Failed cannulation drives repeat procedures, percutaneous or surgical rescue, higher costs, longer hospital stay—and it also increases post-ERCP pancreatitis (PEP)...

Robot-Assisted Gastric ESD Is Feasible and Safe-Endoscopy Feb.26

Introduction Endoscopic submucosal dissection (ESD) is the preferred curative treatment for early gastric cancer, but it remains technically demanding, largely because of poor traction and limited visualization during submucosal dissection. Multiple traction techniques have been...

Cold EMR Is Safer Than Hot EMR for Large Colorectal Polyps-Endoscopy Feb.26

Introduction Endoscopic mucosal resection (EMR) is the standard of care for large (≥20 mm), nonpedunculated colorectal polyps. Over the last few years, cold EMR and thermal ablation–assisted EMR have been increasingly adopted, aiming to reduce...

Even One Pancreatic Duct Cannulation Raises PEP Risk-Endoscopy Feb.25

Introduction Post-ERCP pancreatitis (PEP) remains the most frequent and feared complication of ERCP. We all recognize that repeated pancreatic duct (PD) cannulations increase risk—but in real life, many cases involve just one inadvertent guidewire entry...

Reusable vs Single-Use Duodenoscopes: The Environmental Cost- Endoscopy Feb.26

Introduction Duodenoscope-related infection outbreaks—largely linked to reprocessing failures—drove the development of single-use duodenoscopes to eliminate cross-contamination risk. The safety argument is compelling. But ERCP already sits in a resource- and waste-heavy environment, and healthcare is...

Polyps ≥10 mm Alone: Low PCCRC Risk at 5 Years- Endoscopy Feb.26

Introduction Post-polypectomy surveillance is one of the biggest drivers of colonoscopy workload worldwide. Current guidelines often label any polyp ≥10 mm as “high risk,” triggering a 3-year surveillance colonoscopy. But many endoscopists have questioned whether...

AI in Endoscopy: ESGE Curriculum for Safe Use- Endoscopy Feb. 26

Introduction Artificial intelligence is rapidly entering routine GI endoscopy—particularly for polyp detection, lesion characterization, and quality assurance. While early studies show improved detection and efficiency, AI also introduces new risks: inappropriate trust, cognitive bias, deskilling,...

Regenerative Endoscopy for Refractory GI Wall Defects- Endoscopy Feb.26

Introduction Gastrointestinal wall defects—such as leaks, fistulas, and chronic perforations—remain among the most frustrating complications in GI practice. Even with modern tools (clips, suturing, stents, vacuum therapy), chronic defects with inflamed, fibrotic, retracted margins often...

CADe in endoscopy - Endoscopy Feb. 26

Introduction Colonoscopy quality is often judged by the adenoma detection rate (ADR), because better detection is linked to lower risk of future colorectal cancer. AI-based computer-aided detection (CADe) systems reliably increase ADR in the short...

Colonoscopy-Related Adverse Events in the 21st Century - AJG 2026

The global incidence of colonoscopy-related adverse events (AEs) was analysed through a comprehensive meta-analysis of 82 population-based studies involving 38.5 million colonoscopies across 24 countries. The study categorised AEs into gastrointestinal and nongastrointestinal events. Gastrointestinal...

ESD – does techniques matter?(Endoscopy, Jan-2026)

Yes, techniques for Endoscopic Submucosal Dissection (ESD) matter significantly, as different techniques demonstrate varying advantages and outcomes depending on the clinical scenario. Based on the synthesized evidence from 18 randomized controlled trials (RCTs) involving 2,677...

TOF and endoscopic Occluders(Endoscopy, Jan-2026)

Tracheoesophageal fistulas (TOF) or gastrointestinal (GI)–tracheobronchial fistulas are abnormal connections between the trachea and the esophagus or GI tract. These conditions are often challenging to manage, especially when refractory to conventional treatments. Endoscopic occluders represent...

Endoscopy and Gastric Varices(Endoscopy, Jan-2026)

Role of Endoscopy in Gastric Varices: Endoscopy is a critical tool in the diagnosis and management of gastric varices in patients with cirrhosis. Gastric varices are enlarged veins in the stomach that develop due to...

Photometric Capsule and Emergency Upper Endoscopy(Endoscopy, Jan-2026)

The Photometric Capsule Examination (PCE) is a novel diagnostic tool designed to evaluate suspected nonvariceal upper gastrointestinal hemorrhage (NVUGIH). It is a small, ingestible capsule equipped with sensors and imaging technology that can detect signs...

Esophageal ESD and stricture prevention(GIE, Jan-2026)

The study published in Gastrointestinal Endoscopy (GIE), January 2026 focuses on esophageal endoscopic submucosal dissection (ESD) and strategies for preventing esophageal strictures, a common and serious complication following extensive resections. Below is a detailed summary...

POEM and GERD – dose technique matter? (GIE, Jan-2026)

POEM Techniques and GERD: Does Technique Matter? POEM is a minimally invasive endoscopic procedure used to treat achalasia, a motility disorder of the esophagus. There are two primary techniques for POEM: Full-Thickness (FT) POEM: This...

Green Endoscopy Unit (GIE, Jan-2026)

The Green Endoscopy Unit (GIE) concept, set to launch in January 2026, aims to minimize the environmental impact of endoscopic procedures while maintaining high-quality patient care. Its core strategy revolves around reducing unnecessary activities, emphasizing...

Saline-Immersion Technique for Colorectal ESD: Outcomes From a Western Cohort - J of JGH - Jan,26

The referenced study, "Saline-Immersion Technique for Colorectal ESD: Outcomes From a Western Cohort," published in the Journal of Gastroenterology and Hepatology on January 26, evaluates the use of the saline-immersion/irrigation technique combined with the pocket-creation...

Endoscopic Full-Thickness Resection for Extraluminal Gastric Submucosal Tumors - J of JGH - Jan,26

Based on the context provided, the study on "Endoscopic Full-Thickness Resection (EFTR) for Extraluminal Gastric Submucosal Tumors" likely highlights the feasibility, safety, and clinical outcomes of EFTR as a minimally invasive approach for managing gastric...

Reflux-Related Esophageal Stricture After POEM - J of JGH - Jan,26

Based on the context provided, the study titled "Reflux-Related Esophageal Stricture After POEM" published in the Journal of Gastroenterology and Hepatology (JGH) on January 26 likely focuses on the clinical differentiation between reflux-related esophageal strictures...

ESD Vs TEM for Rectal Polyp

Endoscopic Submucosal Dissection (ESD) and Transanal Endoscopic Microsurgery (TEM) are both minimally invasive techniques used for the treatment of rectal polyps, particularly early-stage rectal cancer or large benign polyps. Comparing ESD and TEM for rectal...

Rapid trypsinogen-2 test and post ERCP discharge Strategy - EJGH Nov 26

The study "Rapid trypsinogen-2 test and post-ERCP discharge strategy" published in the European Journal of Gastroenterology & Hepatology (EJGH) on November 26 explores methods to predict adverse events (AEs) following endoscopic retrograde cholangiopancreatography (ERCP). It...

EUS, TIPS and Cavernous Transformation of the Portal Vein

EUS (Endoscopic Ultrasound), TIPS (Transjugular Intrahepatic Portosystemic Shunt), and Cavernous Transformation of the Portal Vein (CTPV) are interconnected concepts in the management of portal hypertension and its complications, particularly in patients with liver cirrhosis and...

REACT for colorectal ESD

REACT, which stands for Repositionable Elastic Adaptive Customizable Traction, is an innovative traction method designed to assist in Endoscopic Submucosal Dissection (ESD) for colorectal lesions. ESD is a minimally invasive procedure used to remove complex...

ESD for upper esophageal cancer

Endoscopic submucosal dissection (ESD) is increasingly recognized as an effective and minimally invasive treatment option for superficial esophageal squamous neoplasms (ESN), including early-stage esophageal cancer. This technique is particularly suitable for treating superficial lesions confined...

Endoscopic Gastroplasty and weight loss

Endoscopic Gastroplasty (EG) is a minimally invasive procedure designed to help manage obesity by reducing the size of the stomach without requiring traditional surgical methods. It is classified as an Endoscopic Bariatric Therapy (EBT), which...

ESD, Esophageal Stricture and steroid

ESD (Endoscopic Submucosal Dissection): Endoscopic Submucosal Dissection (ESD) is a minimally invasive endoscopic procedure used to treat superficial esophageal cancer. It allows for the precise removal of cancerous lesions while preserving the surrounding healthy tissue....

Endoscopic Billary Drainage in surgically altered anatomy

Endoscopic biliary drainage (BD) in patients with surgically altered anatomy (SAA) is a complex and challenging medical procedure. SAA refers to patients who have undergone surgeries that change the normal anatomy of the gastrointestinal tract,...

EUS-guided gallbladder drainage in acute cholecystitis

EUS-guided gallbladder drainage (EUS-GBD) has emerged as a valuable and reliable treatment option for patients with acute cholecystitis who are considered high-risk for surgical intervention. Acute cholecystitis, an inflammation of the gallbladder typically caused by...

EUS-guided Gallbladder drainage in malignant biliary obstruction

EUS-guided gallbladder drainage (EUS-GBD) is an emerging endoscopic technique used in the management of malignant biliary obstruction (MBO), particularly in cases where conventional approaches like endoscopic retrograde cholangiopancreatography (ERCP) are not feasible or have failed....

EUS - Performance matrix by ESGE

Key takeaways from the European Society of Gastrointestinal Endoscopy (ESGE) guidelines for the performance matrix in endoscopic ultrasound (EUS): Informed Patient Consent: ESGE mandates that informed patient consent must be obtained for 100% of EUS...

Endoscopic papillectomy for laterally spreading lesions of the papilla

Endoscopic papillectomy is a recognized treatment for ampullary lesions, including the rare subtype of laterally spreading lesions (LSLs) of the papilla of Vater. LSLs are characterized by their extensive involvement of the duodenal mucosa, making...

Cyanoacrylate Glue for Gastric Varices

Cyanoacrylate glue is a medical adhesive commonly used in the treatment of gastric varices, particularly in patients with cirrhosis who are experiencing variceal bleeding. Gastric varices are dilated veins in the stomach, which can rupture...

EPOC trial

The EPOC trial (Prophylactic clip closure after ESD of large flat and sessile polyps) is a multicenter randomized controlled trial conducted to evaluate the effectiveness of prophylactic clip closure in reducing delayed bleeding rates following...

Laterally spreading tumors

Laterally spreading tumors (LSTs) are a distinct category of colorectal lesions characterized by their nonpolypoid, flat appearance and their lateral growth pattern rather than vertical growth. These lesions are defined as being at least 1...

Endoscopic Submucosal Dissection for Early Gastric Cancer Using a Novel Bending Attachment

Endoscopic submucosal dissection (ESD) is a minimally invasive technique used for the removal of early-stage gastrointestinal cancers, including early gastric cancer. This procedure allows for precise en bloc resection of lesions while preserving healthy tissue....

Local Recurrence Risk After Horizontal Margin–Positive En Bloc Colorectal ESD

The systematic review and meta-analysis you are referencing provides an in-depth evaluation of the local recurrence risk after en bloc colorectal endoscopic submucosal dissection (ESD) with positive or indeterminate horizontal margins (HM1/x). Here is a...

EUS-Guided Gallbladder vs Bile Duct Drainage for Malignant Biliary Obstruction: Multicenter Trial

The study you are referring to is an international multicenter trial that compared two endoscopic ultrasound (EUS)-guided procedures for managing distal malignant biliary obstruction (MBO): EUS-guided gallbladder drainage (EUS-GBD) and EUS-guided choledochoduodenostomy (EUS-CDS). Traditionally, such...

Prophylactic Rectal ESD Defect Closure and Post-ESD Outcomes

The study explored the impact of prophylactic closure of rectal ESD (endoscopic submucosal dissection) defects on post-ESD outcomes, focusing on delayed adverse events (DAEs) and post-procedure hospitalization. Here are the key findings: Study Details: Objective:...

Efficacy of PEG–Ascorbic Acid Plus Linaclotide vs Senna for Bowel Preparation (APPLE Trial)

The APPLE trial (Efficacy of PEG–Ascorbic Acid Plus Linaclotide vs Senna for Bowel Preparation) was a multicenter, endoscopist-blinded, randomized controlled trial conducted across five centers in Japan. The study aimed to evaluate whether adding linaclotide...

Spray vs Forced Coagulation in ESD for Early Gastric Neoplasms

The comparison between Spray Coagulation Mode (SCM) and Forced Coagulation Mode (FCM) in Endoscopic Submucosal Dissection (ESD) for early gastric neoplasms has been thoroughly investigated in a multicenter randomized controlled trial conducted across five Japanese...

Impact of the S–O Clip on Endoscopic Submucosal Dissection Outcomes: A Meta-Analysis

The meta-analysis on the impact of the S–O clip on Endoscopic Submucosal Dissection (ESD) outcomes provides compelling evidence supporting the clinical benefits of this traction device. Below is a detailed summary of the findings: Background...

Comparative Efficacy and Safety of Endoscopic Modalities for Colorectal Cancer Screening in IBD

The comparative efficacy and safety of endoscopic modalities for colorectal cancer (CRC) screening in patients with inflammatory bowel disease (IBD) have been thoroughly investigated in the modern high-definition (HD) endoscopy era. Below is a detailed...

Systematic endoscopic characterization of synchronous esophageal, gastric, and colorectal involvement in multisystem Langerhans cell histiocytosis

Systematic endoscopic characterization of synchronous esophageal, gastric, and colorectal involvement in multisystem Langerhans cell histiocytosis (LCH) provides critical insights into the rare and under-recognized gastrointestinal (GI) manifestations of this disease. Below is a detailed overview...

Endoscopic characterization of synchronous esophageal, gastric, and colorectal involvement in multisystem Langerhans cell histiocytosis

The endoscopic characterization of synchronous esophageal, gastric, and colorectal involvement in multisystem Langerhans cell histiocytosis (LCH) involves identifying specific patterns and features across the gastrointestinal (GI) tract. This is particularly important as GI involvement in...

ER-STER for cervical esophageal submucosal tumors via PEG

ER-STER (Endoscopic Retrograde Submucosal Tunnel Resection) represents an innovative approach to address the challenges of resecting cervical esophageal submucosal tumors (SMTs), which are difficult to access and treat using conventional endoscopic techniques due to the...

Robotic endoscopic resection

Robotic endoscopic resection refers to the use of robotic systems to perform advanced endoscopic procedures, particularly for the removal of large or complex lesions in the gastrointestinal (GI) tract. One of the most promising applications...

The Boškoski–Costamagna ERCP Trainer

The Boškoski–Costamagna ERCP Trainer is an advanced simulation tool designed to aid novice trainees in developing their skills in Endoscopic Retrograde Cholangiopancreatography (ERCP), a complex endoscopic procedure used to diagnose and treat conditions affecting the...

EUS guided tissue sampling - ESGE statement

The European Society of Gastrointestinal Endoscopy (ESGE) has issued updated statements and recommendations regarding endoscopic ultrasound (EUS)-guided tissue sampling, emphasizing advancements in needle technology, sampling techniques, and specimen handling to optimize diagnostic accuracy. The key...

Single-use therapeutic gastroscope

The single-use therapeutic gastroscope is a newly approved disposable device designed for complex therapeutic interventions in gastrointestinal endoscopy. This pilot feasibility study assessed its clinical performance during 19 therapeutic procedures, including gastrointestinal bleeding management, pancreatic...

MAPS III guideline updates

The MAPS III guideline updates, set for 2025, provide comprehensive, pragmatic, and risk-stratified recommendations for the detection, staging, treatment, and surveillance of gastric precancerous conditions and early gastric neoplasia. Below is a detailed summary of...

Water-aided colonoscopy

Water-aided colonoscopy refers to a set of advanced techniques where water is used instead of, or in combination with, gas (such as air or carbon dioxide) during a colonoscopy procedure. These techniques aim to improve...

Conventional and underwater ESD for superficial colorectal neoplasms

The study compared conventional endoscopic submucosal dissection (CESD) and underwater endoscopic submucosal dissection (UESD) for removing superficial colorectal neoplasms (SCNs). UESD was hypothesized to offer procedural advantages by utilizing buoyancy to lift lesions, potentially reducing...

Origami method for duodenal ESD

The Origami Method (OGM) is a modified double-layered suturing technique developed specifically for closing large mucosal defects following duodenal endoscopic submucosal dissection (ESD). Duodenal ESD is a minimally invasive procedure used to remove lesions or...

POEM training in Europe- ESGE Statement

The European Society of Gastrointestinal Endoscopy (ESGE) has issued a comprehensive Position Statement regarding the training curriculum for performing peroral endoscopic myotomy (POEM) in Europe. POEM is an advanced endoscopic procedure that is now recognized...

Biliary drainage prior to pancreatoduodenectomy with EUS-guided choledochoduodenostomy versus conventional ERCP

The study compared two methods of preoperative biliary drainage for patients undergoing pancreatoduodenectomy: endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) and conventional endoscopic retrograde cholangiopancreatography (ERCP). Preoperative biliary drainage is often necessary but can lead to complications that...

Radical Endoscopic Resection of high risk T1 esophageal adenocarcinoma

Radical Endoscopic Resection (ER) is a minimally invasive procedure that is used to treat early-stage esophageal adenocarcinoma (EAC), specifically high-risk T1 EAC. T1 esophageal adenocarcinoma refers to a cancer that is confined to the innermost...

Gloucester Comfort Scale scores

The Gloucester Comfort Scale (GCS) is a clinician-assessed scoring system used to evaluate patient comfort during procedures such as colonoscopy. It is a 1–5 scale, with higher scores indicating greater discomfort or pain experienced by...

Optical assessment of scars after EMR - STAR-LNPCP Trial

The STAR-LNPCP trial conducted a multicenter study to assess the reliability of optical assessment as a follow-up method for scars after piecemeal endoscopic mucosal resection (EMR) of large colorectal polyps (≥20 mm). The study aimed...

EUS-guided gallbladder drainage in patients with cirrhosis

Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is a minimally invasive procedure that has proven to be safe and effective for treating symptomatic gallbladder disease in patients with cirrhosis. Cirrhotic patients are traditionally considered high-risk for surgical...

Hemostatic powder TC-325 in Maliganant upper GI bleeding

Hemostatic powder TC-325 has emerged as a promising treatment option for malignant upper gastrointestinal bleeding (MUGIB), which is one of the most difficult types of GI bleeding to manage. MUGIB often results from cancer-related lesions...

Bariatric and metabolic endoscopy: ESGE Technical Review

The "Bariatric and Metabolic Endoscopy: ESGE Technical Review" provides a detailed and comprehensive overview of endoscopic bariatric and metabolic therapies (EBMTs), which are minimally invasive treatment options for obesity and related metabolic diseases. The review...

Endoscopic vacuum therapy for nonvariceal UGI bleeding

Endoscopic vacuum therapy (EVT), traditionally used for gastrointestinal perforations and leaks, has shown promising results as a treatment for nonvariceal upper gastrointestinal bleeding (NVUGIB), including cases resistant to standard hemostatic therapies. The following provides detailed...

POEM for symptomatic blown-out myotomy

Blown-out myotomy (BOM) is a structural complication that can occur after a previous myotomy for achalasia, a condition where the esophagus has difficulty moving food into the stomach. In BOM, the original myotomy (a surgical...

In-hospital mortality in patients with lower GI bleeding

In-hospital mortality in patients with lower gastrointestinal bleeding (LGIB) can be significant, depending on various factors. A new tool, the ALIBI score, was developed to predict the risk of death in patients hospitalized with LGIB....

Effects of PPI on LAMS occlusion rate following pancreatic necrosectomies

This study explored the impact of proton pump inhibitors (PPIs) on lumen-apposing metal stent (LAMS) occlusion rates in patients undergoing pancreatic necrosectomy for walled-off necrosis (WON). LAMS are used to drain infected or necrotic fluid...

Endoscopic surveillance recommendations for Barrett's Esophagus - AGA View

The American Gastroenterological Association (AGA) provides detailed recommendations for endoscopic surveillance in patients with Barrett’s Esophagus (BE). Below is a comprehensive summary of the AGA's guidelines based on the context provided: Surveillance for Nondysplastic Barrett’s...

Endoscopic Nasobiliary Drainage for Type 1 Autoimmune Pancreatitis

Endoscopic Nasobiliary Drainage (ENBD) is a minimally invasive procedure used to drain bile from the biliary system to relieve jaundice or other complications caused by bile duct obstruction. A small catheter is placed through the...

Endocytoscopy

Endocytoscopy is an advanced, high-resolution imaging technique used in medical diagnostics, particularly in the field of gastroenterology and oncology. It is a form of ultra-high magnification endoscopy that allows clinicians to visualize cellular and subcellular...

Confocal Laser Endoscopy

Confocal Laser Endoscopy is an advanced imaging technique that combines the principles of confocal microscopy and endoscopy to provide high-resolution, real-time visualization of tissues at the cellular and subcellular levels. It is particularly useful in...

EUS and EUS Elastography

Endoscopic Ultrasound (EUS) and EUS Elastography are advanced diagnostic techniques used primarily in gastroenterology to evaluate and characterize lesions in the gastrointestinal tract and surrounding structures. While they are related, they differ significantly in their...

EMR-L versus ESD in treating small gastric stromal tumors

Endoscopic ligator-assisted mucosal resection (EMR-L) and endoscopic submucosal dissection (ESD) are two techniques used to treat small gastric stromal tumors (GSTs). Here's a detailed comparison based on the context provided: --- What are Small Gastric...

Predicting endoscopic hemostasis failure in esophageal variceal bleeding

The study aimed to develop and validate a predictive nomogram for assessing the risk of endoscopic hemostasis failure in cirrhotic patients presenting with acute esophagogastric variceal bleeding (EGVB). EGVB is a severe complication of portal...

Purastat and its role Upper GI bleeding

Purastat is an innovative and promising hemostatic agent specifically designed for the management of upper gastrointestinal bleeding (UGIB), particularly non-variceal UGIB. It is a synthetic peptide-based gel that belongs to the class of self-assembling peptide...

Traction techniques in endoscopic submucosal dissection (ESD)

Traction techniques in endoscopic submucosal dissection (ESD) play a crucial role in improving procedural outcomes, safety, and feasibility, particularly in Western settings where ESD adoption has faced challenges. These techniques act as a mechanical "third...

Predicting mortality and readmission in UGIB

This study aimed to assess the accuracy of three pre-endoscopic scoring systems—Glasgow-Blatchford Score (GBS), AIMS65, and pre-endoscopic Rockall Score (pRS)—in predicting 30-day mortality and hospital readmission in patients with upper gastrointestinal bleeding (UGIB) in Iranian...

Efficacy of 200 mg vs 1200 mg Simethicone with 3 L PEG for Afternoon Colonoscopy.

This study compared the effectiveness of 200 mg versus 1200 mg simethicone (SIM) added to 3 L polyethylene glycol electrolyte solution (PEG-ELS) for afternoon colonoscopy preparation. Conducted at Shenzhen People’s Hospital between February and July...

A new horizon of endoscopic anti-reflux therapy

The new horizon of endoscopic anti-reflux therapy is exemplified by the emergence of Anti-Reflux Mucosal (ARM) interventions, which include anti-reflux mucosectomy (ARMS), mucosal ablation (ARMA), and mucoplasty (ARMP). These techniques represent a groundbreaking advancement in...

ERCP Complications

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a critical therapeutic procedure for managing pancreaticobiliary diseases, but it is associated with significant risks. Below is a detailed overview of ERCP complications, including their incidence, risk factors, prevention strategies,...

Endoscopic management of NVNPUB - A Canadian Guideline

The Canadian Association of Gastroenterology (CAG), in collaboration with international experts, has developed evidence-based guidelines specifically for the endoscopic management of nonvariceal, nonpeptic ulcer upper gastrointestinal bleeding (NVNPUB). This guideline addresses bleeding caused by conditions...

Endoscopic Balloon Dilation in IBD

Endoscopic balloon dilation (EBD) is a minimally invasive procedure used in the management of intestinal strictures in patients with inflammatory bowel disease (IBD), particularly Crohn’s disease (CD). Strictures are areas of narrowing in the gastrointestinal...

VS System for diagnosing early gastric cancer

VS Classification System for Diagnosing Early Gastric Cancer The VS Classification System is a standardized diagnostic approach designed to detect early gastric cancer (EGC) using Narrow Band Imaging (NBI), a specialized endoscopic imaging technology. This...

Speed Boat Device - Novel Resection Technique

The Speedboat RS2 device, developed by Creo Medical Ltd, is an advanced bipolar electrosurgical tool designed for minimally invasive endoscopic procedures like Endoscopic Submucosal Dissection (ESD) and Peroral Endoscopic Myotomy (POEM). It features a 4.2-mm...

EndoFLIP

EndoFLIP (Endolumenal Functional Lumen Imaging Probe): A Comprehensive Overview EndoFLIP is an advanced diagnostic tool designed to measure esophageal distensibility and sphincter compliance in real time. It is a highly specialized instrument that complements high-resolution...

Efficacy and Safety of ARMS versus Stretta in GERD

The comparison of Anti-Reflux Mucosectomy (ARMS) and Radiofrequency Ablation (Stretta) for the treatment of Gastroesophageal Reflux Disease (GERD) highlights differences in efficacy and safety profiles. Here's a detailed breakdown based on the systematic review and...

Endoscopic Sleeve Gastroplasty on Obesity-Related Comorbidities

Endoscopic Sleeve Gastroplasty (ESG) has shown significant promise in managing obesity-related comorbidities, as evidenced by a prospective 5-year study. Here are the key findings related to its impact: Weight Loss Patients undergoing ESG achieved an...

Post ERCP-Induced Perforation

Endoscopic retrograde cholangiopancreatography (ERCP)-induced perforation is a rare but serious complication that requires prompt diagnosis and appropriate management to minimize morbidity and mortality. Management strategies are guided by the type and severity of the perforation,...

pHoenix Score for GERD Using 24-Hour pH Monitoring

The pHoenix Score (pHx-S) is a novel diagnostic metric developed to enhance the accuracy of diagnosing gastroesophageal reflux disease (GERD) using 24-hour pH monitoring. It addresses limitations of traditional methods like acid exposure time (AET)...

Nissen fundoplication versus Toupet fundoplication on postoperative manometry findings

When comparing Nissen fundoplication (LNF) and Toupet fundoplication (LTF) based on postoperative manometry findings, the following distinctions emerge: Improvement in LES Pressure: Both Nissen and Toupet fundoplications significantly increase lower esophageal sphincter (LES) pressure after...

Blown-Out Myotomy (BOM)

Blown-Out Myotomy (BOM): Blown-Out Myotomy (BOM) is a relatively rare but significant complication that can occur after undergoing Peroral Endoscopic Myotomy (POEM), a minimally invasive procedure used to treat esophageal motility disorders such as achalasia....