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POEM for symptomatic blown-out myotomy

Clinical knowledge base written and curated by GastroAGI Team from primary medical literatureLast updated November 1, 2025

Blown-out myotomy (BOM) is a structural complication that can occur after a previous myotomy for achalasia, a condition where the esophagus has difficulty moving food into the stomach. In BOM, the original myotomy (a surgical cut in the esophageal muscles to improve swallowing) fails or disrupts, leading to poor esophageal emptying and a recurrence of symptoms like difficulty swallowing, chest pain, or regurgitation. When these symptoms significantly impact a patient’s quality of life, it is referred to as symptomatic blown-out myotomy.

Peroral Endoscopic Myotomy (POEM) is a minimally invasive endoscopic procedure that is used as a salvage treatment for symptomatic BOM. During POEM, a flexible endoscope is inserted through the mouth to access the esophagus. The surgeon creates a tunnel in the esophageal lining and cuts the problematic muscle layers to restore proper esophageal function.

The study found that POEM is both safe and effective for treating symptomatic BOM. It had a low rate of complications, even in anatomically altered cases like BOM. Clinical success was high (85.7% at 2 years), meaning most patients experienced significant symptom relief. This makes POEM a reliable option for patients with recurrent achalasia symptoms due to BOM, helping them regain better swallowing and quality of life.

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