Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
The FITCH trial investigated the efficacy of bezafibrate, a broad peroxisome proliferator-activated receptor (PPAR) agonist, in alleviating moderate to severe pruritus in patients with fibrosing cholangiopathies, including primary...
The RESPONSE trial was a pivotal phase 3 study designed to evaluate the efficacy and safety of seladelpar, a selective peroxisome proliferator–activated receptor delta (PPARδ) agonist, in patients...
The ELATIVE trial was a clinical study designed to evaluate the efficacy and safety of elafibranor, a dual PPAR-α/δ agonist, as a potential second-line treatment for primary biliary...
The POISE study is a phase 3 clinical trial designed to evaluate the efficacy and safety of obeticholic acid (OCA), a farnesoid X receptor (FXR) agonist, in patients...
The COBALT Trial was a significant clinical study aimed at evaluating the long-term clinical benefits of obeticholic acid (OCA) in the treatment of primary biliary cholangitis (PBC), a...
The Question Prompt List (QPL) for Primary Biliary Cholangitis (PBC) is a standardized tool designed to enhance physician-patient communication, improve patient engagement in care, and optimize health outcomes...
Portal vein thrombosis (PVT) is a significant complication in patients with liver cirrhosis (LC), as it exacerbates portal hypertension and accelerates progression toward decompensation. Risk factors for PVT...
The CORE model, developed by researchers at Karolinska Institutet, predicts the 10-year risk of developing severe liver diseases, such as cirrhosis and liver cancer, using a simple blood...
Antibiotic Prophylaxis in Gastrointestinal (GI) Bleeding in Cirrhosis: A Comprehensive Overview Antibiotic prophylaxis has been a cornerstone in the management of cirrhotic patients with upper gastrointestinal (GI) bleeding...
The ultra-early predictive model for Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) is a promising development in preventive healthcare. This model relies on identifying specific protein changes in the...
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