Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
What Did the Study Find? This pragmatic RCT randomized 216 hospitalized patients with ACLF and predefined risk factors for invasive fungal infection (IFI) to immediate empirical antifungal therapy...
Introduction: Statins have been associated with potential hepatic benefits in compensated cirrhosis, but whether they improve outcomes after MASLD cirrhosis has already decompensated remains uncertain. This study examined...
Introduction: Baveno criteria have transformed non-invasive diagnosis of clinically significant portal hypertension (CSPH), but many patients remain in an indeterminate “gray zone.” The ELASTO-ML study developed a machine-learning...
Introduction: After variceal haemorrhage, secondary prophylaxis with nonselective beta-blockers (NSBBs) plus endoscopic variceal ligation (EVL) is standard. However, prognosis may differ substantially according to the patient’s previous pattern...
Introduction: Distinguishing MASLD, MetALD and alcohol-associated liver disease (ALD) depends heavily on self-reported alcohol intake, which is vulnerable to underreporting. This prospective study evaluated phosphatidylethanol (PEth) as an...
Introduction: Patients with alcohol-related cirrhosis and non-acute decompensation (NAD) may appear sufficiently stable for outpatient management but remain at substantial risk of rapidly progressing to hospitalisation-requiring acute decompensation...
Introduction: Acute-on-chronic liver failure (ACLF) is a high-mortality syndrome characterised by acute deterioration of chronic liver disease with organ dysfunction or failure. Yet, unlike conditions such as sepsis...
Hepatic encephalopathy (HE) is usually diagnosed through clinical assessment and psychometric testing, but these approaches can be time-consuming and require trained personnel. LivSens is a portable multisensor breath-analysis...
Introduction: Current assessment of chronic liver disease relies largely on static biomarkers and structural measurements such as laboratory scores, elastography, imaging, and liver biopsy. However, fibrosis severity does...
Introduction: Hyponatremia is common in advanced cirrhosis, particularly in patients with ascites, and reflects impaired free-water excretion due to effective arterial underfilling rather than true sodium depletion in...
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