Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction: Distinguishing benign from malignant biliary strictures remains one of the greatest challenges in pancreatobiliary endoscopy. Although ERCP brush cytology and biopsy have excellent specificity, their sensitivity is...
Introduction: Pancreatic enzyme replacement therapy (PERT) is the standard treatment for exocrine pancreatic insufficiency (EPI) but is currently derived exclusively from porcine pancreatic extracts, requiring multiple capsules and...
Introduction: Accurate tumour segmentation is fundamental for precision oncology, enabling objective assessment of tumour burden, treatment response, and radiomics analysis. This study developed and validated an anatomically constrained...
Introduction: The widespread detection of intraductal papillary mucinous neoplasms (IPMNs) has substantially increased surveillance programs, although only a small proportion progress to pancreatic cancer. This study evaluated the...
Introduction: Robotic cholecystectomy continues to expand worldwide, but its value compared with conventional laparoscopy remains debated. This large study evaluated whether the robotic platform offers meaningful clinical or...
Introduction: Advanced cholangiocarcinoma (CCA) remains difficult to treat, with limited benefit from current chemotherapy and immunotherapy combinations. This study investigated whether combining a MEK inhibitor (MEKi), anti-PD-L1 therapy,...
Introduction: Advanced biliary tract cancer (BTC) carries a poor prognosis, with limited improvements in survival despite the addition of immune checkpoint inhibitors to standard gemcitabine–cisplatin chemotherapy. This phase...
Introduction: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become a cornerstone in the management of type 2 diabetes because of their excellent glycemic, cardiovascular, and weight-loss benefits. However,...
Introduction: Patients undergoing pancreatoduodenectomy for non invasive intraductal papillary mucinous neoplasm (IPMN) require long-term surveillance because of the risk of disease recurrence in the pancreatic remnant. New pancreatic...
This study evaluated 1,063 patients undergoing pancreatic surgery; 11% developed conventionally defined chyle leak. Most clinically relevant cases were grade B, while no grade C leaks were reported....
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