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Trending Topics in Gastroenterology

Explore current gastroenterology questions, clinical answers, and emerging research by topic.

01

GRWR Alone Does Not Explain Small-for-Size Risk After LDLT: Liver Transplantation | doi:10.1097/LVT.0000000000001022

What Did the Study Find? This prospective international registry analysis included 1,944 living donor liver transplants at 55 centres between September 2023 and February 2025. Recipients were grouped...

02

ICI-Based Downstaging Before Liver Transplant: JAMA Oncology | October 2026

What Did the Study Find? This study examined whether immune checkpoint inhibitor (ICI)-based multimodal therapy before liver transplantation can improve outcomes in selected patients with HCC initially beyond...

03

Does MELD Over-Prioritize Alcohol-Associated Hepatitis for Liver Transplantation?: Liver Transplantation | September 2026

What Did the Study Find? Using US national UNOS data from 2018–2024, investigators compared transplant candidates with alcohol-associated hepatitis (AAH), other alcohol-associated liver disease (ALD), and non-ALD indications....

04

ACLF-3 Liver Transplantation: Can TAM or SALT-M Reliably Decide Who Should Be Transplanted?: Liver Transplantation | September 2026

What Did the Study Find? This international study evaluated 336 patients transplanted with ACLF grade 3 across nine cohorts to assess the TAM and SALT-M scores for predicting...

05

Improving Medication Adherence After Liver Transplantation: Liver Transplantation | August 2026

Introduction: Long-term adherence to immunosuppression is essential after liver transplantation, yet medication nonadherence remains an important preventable cause of poor graft and patient outcomes. This systematic review and...

06

Prioritizing Low-Risk HCC Patients for Liver Transplant May Worsen Waitlist Outcomes for Higher-Risk Candidates: Liver Transplantation | July 2026

Introduction: Liver transplantation (LT) offers the greatest survival benefit for patients with hepatocellular carcinoma (HCC) at high risk of disease progression while awaiting transplant. However, current allocation policies...

07

Behavioural Alcohol Use Disorder Therapy During Liver Transplant Evaluation: Liver Transplantation | July 2026

Introduction: Liver transplantation is increasingly being offered to carefully selected patients with alcohol-associated liver disease (ALD) who have less than six months of sobriety. This multicenter study evaluated...

08

Bilateral Duct-to-Duct Reconstruction in Dual Left Graft LDLT: Liver Transplantation | July 2026

Introduction: In dual left graft living donor liver transplantation (LDLT), reconstruction of the bile ducts is technically demanding because rotation of the right-sided graft alters the anatomical relationship...

09

Liver Transplantation After Chemotherapy and SIRT for Unresectable Intrahepatic Cholangiocarcinoma: Journal of Hepatology | July 2026

Introduction: Liver transplantation (LT) has traditionally not been recommended for unresectable intrahepatic cholangiocarcinoma (iCCA) because of historically poor outcomes. This study evaluated whether neoadjuvant chemotherapy combined with selective...

10

Predicting Liver Failure After Locoregional Therapy: Liver Transplantation | May 2026

Introduction: Locoregional therapy (LRT) is a cornerstone treatment for early- and intermediate-stage hepatocellular carcinoma (HCC), but post-procedure liver dysfunction remains a major concern. This study evaluated which pre-treatment...

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