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Trending Topics in Gastroenterology

Explore current gastroenterology questions, clinical answers, and emerging research by topic.

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Plasma metabolomics prevents MASH related mortality

Plasma metabolomics, a branch of metabolomics focused on analyzing small molecules (metabolites) in blood plasma, plays a promising role in the prevention of metabolic dysfunction-associated steatohepatitis (MASH) and...

72

Exosome-related genes for MASLD-related HCC

Exosome-related genes have gained significant attention for their potential role in the progression of metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as NAFLD) to hepatocellular carcinoma (HCC)....

73

Normal ALT, Liver Fibrosis and MASLD

The study you provided investigates the relationship between normal ALT (alanine transaminase) levels, liver fibrosis, and metabolic dysfunction-associated steatotic liver disease (MASLD). Here's a detailed breakdown of the...

74

Rapamycin alleviate intrahepatic inflammation in MASLD

Yes, rapamycin alleviates intrahepatic inflammation in metabolic dysfunction-associated steatotic liver disease (MASLD). According to the study, rapamycin's therapeutic effects are primarily mediated through its action on bone marrow-derived...

75

Fisetin against the development of MAFLD

Fisetin, a natural flavonoid found in fruits and vegetables like strawberries and apples, has shown significant potential in combating metabolic dysfunction-associated fatty liver disease (MAFLD). MAFLD, a chronic...

76

Survodutide - Role in MASH

Survodutide is emerging as a promising treatment for metabolic dysfunction–associated steatohepatitis (MASH), a progressive form of metabolic dysfunction–associated steatotic liver disease (MASLD). Survodutide functions as a dual agonist...

77

Efruxifermin and MASH

Efruxifermin (EFX) is a promising treatment for metabolic dysfunction-associated steatohepatitis (MASH), a severe progression of metabolic liver disease with limited effective therapies. EFX is a fibroblast growth factor...

78

Rising Global Burden of MASLD

The global burden of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), formerly known as NAFLD, is rising at an alarming rate and poses a significant public health challenge. MASLD...

79

Spleen-To-Liver Stiffness Ratio in MASH

The spleen-to-liver stiffness ratio (SSM/LSM) is an emerging noninvasive biomarker that has shown significant potential in characterizing portal hypertension (PH), particularly in patients with metabolic dysfunction-associated steatohepatitis (MASH)....

80

GLP-1 and GLP-1/GIP Agonists, Adverse Liver Outcomes and Type 2 DM

GLP-1 receptor agonists (such as semaglutide and liraglutide) and the dual GLP-1/GIP receptor agonist tirzepatide have been studied for their impact on major adverse liver outcomes (MALO) in...

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