Introduction:
For decades, low-to-moderate alcohol consumption has been considered by some to offer potential cardiovascular benefits. This comprehensive U.S. modeling study re-evaluated the lifetime health impact of alcohol consumption using contemporary cause-specific data on alcohol-related diseases and injuries.
Why was this study needed?
Current drinking recommendations remain controversial because many previous studies suggested a protective effect of moderate alcohol intake. Updated evidence was needed to quantify the lifetime risks associated with different drinking levels and patterns.
What did the study show?
- No overall protective health benefit was observed, even at low levels of alcohol consumption.
- Alcohol-related mortality and morbidity increased progressively with increasing weekly alcohol intake.
- Lifetime alcohol-attributable mortality exceeded 1 in 1,000 at approximately 7 drinks per week.
- At around 8–9 drinks per week, the lifetime risk increased to more than 1 in 100.
- Men consuming 14 drinks per week had an estimated 1 in 25 (4%) lifetime risk of dying from an alcohol-attributable cause.
- Drinking more than one drink per occasion further increased the risks of breast cancer, cardiovascular disease, and injuries.
- The findings support limiting alcohol intake to no more than one standard drink per day for both men and women.
Clinical Impact:
These findings challenge the long-held perception that moderate alcohol consumption is beneficial. Clinicians should counsel patients that alcohol-related health risks begin at relatively low levels of intake and increase further with higher weekly consumption and binge drinking patterns.
Take-Home Message:
This large U.S. study found no net health benefit from low-to-moderate alcohol consumption. Alcohol-related health risks rise progressively with increasing intake, supporting a simple public health message: less alcohol is better, and if consumed, intake should ideally be limited to one drink or less per day.