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Trending Topics in Gastroenterology

Explore current gastroenterology questions, clinical answers, and emerging research by topic.

151

T1 CRC and ESD(GIE, Jan-2026)

T1 Colorectal Cancer (CRC) T1 CRC refers to early-stage colorectal cancer where the tumor has invaded the submucosa but has not yet spread further. It is subdivided into...

152

Novel Therapeutic approach for pancreatic cancer(GIE,Jan-2026)

The novel therapeutic approach for pancreatic cancer, as detailed in the study published in Gastrointestinal Endoscopy (GIE), January 2026, involves the combination of intratumoral phosphorus-32 (32P) implantation with...

153

Screening for Esophageal Cancer

Screening for esophageal cancer is a critical strategy to improve early detection and survival rates, given the disease's poor prognosis due to late-stage diagnosis. However, effective screening approaches...

154

Glecirasib with or without Cetuximab in previously treated CRC with KRAS mutation - Lancet Gastroenterol Hepatol

The study published in Lancet Gastroenterology & Hepatology investigates the efficacy and safety of glecirasib (JAB-21822), a novel covalent small molecule KRASG12C inhibitor, as monotherapy or in combination...

155

New Drugs for hepatobiliary Cancers - J of Hepatology - Jan.26

The treatment of hepatobiliary cancers, including hepatocellular carcinoma (HCC) and biliary tract cancer (BTC), is undergoing significant advancements with the development of novel drugs and therapeutic strategies. These...

156

Tumour Microenvironment in ICC

The tumor microenvironment (TME) in intrahepatic cholangiocarcinoma (iCCA) plays a pivotal role in tumor progression, immune evasion, and therapeutic resistance. iCCA is characterized by a highly complex and...

157

Chines Expert Consensus of GIST

The Chinese Expert Consensus on Diagnosis and Treatment of Small Gastrointestinal Stromal Tumors (GISTs) is a comprehensive guideline developed by the CSCO Gastrointestinal Stromal Tumor Committee in collaboration...

158

Chemotherapy for Locally Advanced Pancreatic Cancer After NEOPAN: David vs Goliath

The title “Chemotherapy for Locally Advanced Pancreatic Cancer After NEOPAN: David vs Goliath” appears to metaphorically frame the debate between different treatment paradigms for locally advanced pancreatic cancer...

159

Short-Course Radiotherapy for Older Patients With Locally Advanced Rectal Cancer (SOFT Study)

The Short-Course Radiotherapy (SCRT) for Older Patients With Locally Advanced Rectal Cancer (SOFT Study) is a multicenter investigation focused on evaluating the effectiveness and feasibility of SCRT followed...

160

Immune Checkpoint Inhibitor–Induced Diabetes in PD-1/PD-L1 Cancer Trials

Immune Checkpoint Inhibitor–Induced Diabetes (ICI-D) is a rare yet serious immune-related adverse event that can arise in patients undergoing cancer immunotherapy, specifically in clinical trials involving programmed cell...

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