Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction: Acute infectious gastroenteritis can trigger persistent gastrointestinal symptoms long after the infection has resolved, leading to post-infection disorders of gut-brain interaction (PI-DGBI). This global Rome Foundation study...
Introduction: Gut microbiota alterations have been implicated in the pathogenesis of irritable bowel syndrome (IBS), making fecal microbiota transplantation (FMT) a promising therapeutic strategy. However, clinical trials have...
Introduction: Laparoscopic adhesiolysis offers several short-term advantages over open surgery for adhesive small bowel obstruction (ASBO). However, its long-term impact on recurrence, quality of life, and incisional hernia...
Introduction: Growing evidence suggests that Parkinson's disease (PD) may originate in the gut, with pathological α-synuclein spreading to the brain through the vagus nerve. This study investigated whether...
Introduction: Necrotizing enterocolitis (NEC) is one of the most serious gastrointestinal emergencies in neonates. Early identification of infants requiring surgical intervention is critical but remains challenging. This study...
Introduction: Antibiotic exposure is the best-established risk factor for Clostridioides difficile infection (CDI). However, the contribution of many commonly prescribed non-antibiotic medications has remained uncertain. This large Swedish...
Dyssynergic defecation is commonly evaluated using anorectal manometry, traditionally performed in the left lateral decubitus position. However, defecation normally occurs in the seated position, raising questions about whether...
Somatostatin receptor (SSTR) imaging with ⁶⁸Ga-DOTATATE PET is a cornerstone for well-differentiated neuroendocrine tumors, but its role in poorly differentiated neuroendocrine carcinoma (NEC) has remained uncertain. Previous retrospective...
Introduction: The gut microbiome plays a central role in colorectal cancer (CRC) development, influencing inflammation, metabolism, immune responses, and tumor behavior. While several microbial species have been implicated...
Retatrutide is a once-weekly injectable triple hormone receptor agonist targeting GIP, GLP-1, and glucagon receptors. TRANSCEND-T2D-1 evaluated retatrutide as monotherapy in adults with type 2 diabetes inadequately controlled...
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