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Most used

21
MELD-NaAssesses the severity of chronic liver diseaseChild-Pugh ScoreAssesses the prognosis of chronic liver disease, mainly cirrhosisFIB-4 IndexLiver fibrosis scoring indexAPRIAST to platelet ratio — liver fibrosisMaddrey's DFAlcoholic hepatitis severityGlasgow-BlatchfordUpper GI bleed risk stratificationGAHSGlasgow alcoholic hepatitis scoreMontreal IBDIBD classification — CD & UCMayo ScoreUlcerative colitis activityBISAP ScoreBedside index for severity of pancreatitisCLIF-SOFAOrgan failure scoring in cirrhosisAlcohol ContentStandard drinks & alcohol grams calculatorAARC-ACLFAcute-on-chronic liver failure gradePELD / CR ScorePediatric end-stage liver diseaseHarvey-BradshawCrohn's disease activity indexCTSICT severity index — pancreatitisRockall ScoreGI bleed rebleeding & mortality riskCAGEAlcohol use disorder screening (4 questions)MELD 3.0Updated MELD — sex-inclusive formulaAUDIT ScoreAlcohol use disorders identification testVOCAL-Penn ScorePost-operative mortality risk in cirrhosis surgery

Liver & Cirrhosis

17
ALBI GradeAlbumin-bilirubin liver function grade in HCCUKELD ScoreUK model for end-stage liver diseaseMELD-XIMELD excluding INR — for anticoagulated patientsWest Haven CriteriaHepatic encephalopathy gradingMilan CriteriaLiver transplant eligibility in hepatocellular carcinomaLI-RADS v2018 (CT/MRI)Liver observation category from size, APHE and major featuresBCLC StagingHepatocellular carcinoma stage and treatment allocationSimplified AIH CriteriaSimplified criteria for autoimmune hepatitisRevised Original AIH ScoreIAIHG 1999 comprehensive autoimmune hepatitis scoreSAAGSerum-ascites albumin gradient — cause of ascitesR FactorHepatocellular vs cholestatic pattern in liver injuryCLIF-C ACLFMortality prediction in acute-on-chronic liver failureKing's College CriteriaTransplant criteria in acute liver failureGALAD ScoreHCC detection from gender, age, AFP-L3, AFP and DCPMetroticket 2.0AFP-adjusted up-to-seven for HCC transplant eligibilityRUCAMCausality in drug- and herb-induced liver injuryBaveno VII CriteriacACLD, CSPH and sparing screening endoscopy

Fibrosis & MASLD

8
NAFLD Fibrosis ScoreAdvanced fibrosis probability in MASLD/NAFLDBARD ScoreBMI, AST/ALT ratio, diabetes — MASLD fibrosisFatty Liver IndexPredicts hepatic steatosis from routine labsFibrotic NASH Index (FNI)At-risk NASH probability from AST, HbA1c and HDLNAFLD Activity Score (NAS)Histologic activity grade — steatosis, inflammation, ballooningMEFIB IndexMRE + FIB-4 rule for significant fibrosis (≥F2) in MASLDFAST ScoreFibroScan-AST — at-risk NASH from LSM, CAP and ASTSAFE ScoreSteatosis-Associated Fibrosis Estimator for MASLD in primary care

Pancreas & Biliary

8
Ranson's CriteriaAcute pancreatitis severity at 48 hoursGlasgow-Imrie CriteriaAcute pancreatitis severity — the PANCREAS criteriaHAPSHarmless acute pancreatitis scoreTokyo Guidelines — CholangitisTG18 diagnosis and severity grade for acute cholangitisTokyo Guidelines — CholecystitisTG18 diagnosis and severity grade for acute cholecystitisBiliary Pain (Rome IV)Rome IV — defining biliary-type pain before interventionFunctional Pancreatic SODRome IV — pancreatic sphincter of Oddi disorderRevised Atlanta ClassificationAcute pancreatitis severity — mild, moderately severe, severe

IBD

9
Truelove & Witts CriteriaAcute severe ulcerative colitis — admission decisionUCEISUlcerative colitis endoscopic index of severitySCCAISimple clinical colitis activity index — symptoms onlyCDAICrohn's disease activity index — the trial standardSES-CDEndoscopic severity in Crohn's diseasePUCAIPaediatric ulcerative colitis activity indexTravis (Oxford) CriteriaDay 3 colectomy risk in acute severe ulcerative colitisHo IndexDay 3 steroid failure risk in acute severe ulcerative colitisRutgeerts ScorePostoperative Crohn's recurrence at ileocolonoscopy

GI Bleeding

7
EVendo ScorePredicts oesophageal varices needing treatmentForrest ClassificationPeptic ulcer bleeding — rebleeding risk at endoscopyAIMS65 ScoreUpper GI bleed mortality — five bedside criteriaOakland ScoreSafe-discharge risk for acute lower GI bleedingABC ScoreAge, blood tests, comorbidities — GI bleed mortalitySarin ClassificationEndoscopic classification of gastric varicesEGUS (Gastric Ulcer)Malignancy risk in a gastric ulcer, and who needs repeat endoscopy

Alcohol

2
ABIC ScoreAge, bilirubin, INR, creatinine — alcoholic hepatitisLille ModelSteroid response at day 7 in alcoholic hepatitis

Upper GI

4
Chicago Classification v4.0Oesophageal motility pattern from high-resolution manometryLA Classification (Oesophagitis)Los Angeles grade A–D for erosive oesophagitisPrague C & M CriteriaCircumferential and maximal extent of Barrett's oesophagusEREFS (Eosinophilic Oesophagitis)Endoscopic reference score — oedema, rings, exudates, furrows, stricture

Colorectal

3
Boston Bowel Prep ScaleColonoscopy preparation adequacy by segmentStool Osmotic GapOsmotic vs secretory diarrhoea from stool electrolytesATLAS Score (C. difficile)Predicted response to therapy in Clostridioides difficile infection

Functional GI

37
Bristol Stool ScaleStool form types 1–7 and colonic transitRome IV Criteria for IBSIrritable bowel syndrome diagnosis and subtypeFunctional ConstipationRome IV — two of six items, IBS excludedOpioid-Induced ConstipationRome IV — constipation tied to opioid therapyFunctional DiarrhoeaRome IV — loose stools without predominant painFunctional Bloating / DistensionRome IV — bloating without other bowel disorder criteriaUnspecified Functional Bowel DisorderRome IV — bowel symptoms fitting no other categoryCentrally Mediated Abdominal Pain (CAPS)Rome IV — continuous pain unrelated to gut eventsNarcotic Bowel SyndromeRome IV — opioid-induced hyperalgesia of the gutFaecal Incontinence (Rome IV)Rome IV — the criteria, and why nobody is askedFunctional Anorectal PainLevator ani, unspecified pain and proctalgia fugaxFunctional Defecation DisordersRome IV — dyssynergia and inadequate propulsionInfant RegurgitationRome IV — the happy spitter, and the alarm features that rule it outInfant ColicRome IV — recurrent unexplained crying in a well infant under 5 monthsInfant DyscheziaRome IV — straining before a soft stool, and why not to intervenePaediatric Functional ConstipationRome IV — two of six over one month, with overflow soiling as a criterionToddler's DiarrhoeaRome IV functional diarrhoea of childhood — painless, thriving childPaediatric Cyclic Vomiting SyndromeRome IV — both age bands, with different criteria for eachPaediatric Rumination SyndromeRome IV — infant and child/adolescent criteriaFunctional Nausea & Vomiting (Children)Rome IV — two separate disorders that can be met togetherAerophagiaRome IV — distension that increases through the dayPaediatric Functional DyspepsiaRome IV — four times a month, with PDS and EPS subtypingPaediatric Irritable Bowel SyndromeRome IV — plus the constipation clause clinicians missAbdominal MigraineRome IV — stereotypical incapacitating episodes weeks apartFunctional Abdominal Pain — NOSRome IV — the residual category, reached after the other threeNonretentive Faecal IncontinenceRome IV — soiling without retention, where laxatives make it worseFunctional DyspepsiaRome IV — with PDS and EPS subtypingRumination SyndromeRome IV — effortless regurgitation without retchingCyclic Vomiting SyndromeRome IV — stereotypical episodic vomitingCannabinoid HyperemesisRome IV — CVS pattern relieved by cannabis cessationChronic Nausea & VomitingRome IV — chronic nausea and vomiting syndromeBelching DisordersRome IV — supragastric vs gastric belchingFunctional HeartburnRome IV — heartburn with normal acid exposureReflux HypersensitivityRome IV — normal acid exposure, positive symptom associationFunctional Chest PainRome IV — non-cardiac, non-reflux chest painGlobusRome IV — painless lump-in-throat sensationFunctional DysphagiaRome IV — dysphagia with normal endoscopy and manometry
  1. Calculators
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  3. Abdominal Migraine
Functional GI

Abdominal Migraine

Rome IV — stereotypical incapacitating episodes weeks apart

The longest duration rule in the paediatric chapters, and a deliberate exception.

One hour minimum. Rome IV also requires the pain to be the dominant symptom, not one of several.

Long, symptom-free intervals. Daily or weekly pain is a different disorder.

Two of the six. Pallor is the one caregivers describe most vividly and clinicians ask about least.

Six months, not two — the only disorder in the child and adolescent chapter to keep the longer window, because the episodes are separated by weeks to months and a shorter window would not capture the pattern.

When to use
Use it in a child with recurrent severe abdominal pain who is completely well between attacks and whose parents can describe the episodes with unusual precision. That precision is itself a clue: families of children with abdominal migraine typically know the hour it starts, how long it lasts, and what the child looks like — and pallor is the detail they volunteer most vividly and that clinicians ask about least. It is worth considering specifically in a child who has been to the emergency department several times with a normal abdomen each time.
Why use it
Because abdominal migraine is treatable in a way that unlabelled recurrent abdominal pain is not. Recognising it opens two doors: migraine prophylaxis where episodes are frequent enough to justify it, and migraine-style abortive treatment of individual attacks, both of which are entirely unavailable to a child carrying no diagnosis. The other reason is the family history — most affected children have a first-degree relative with migraine, and once the link is drawn the diagnosis usually makes immediate sense to a parent who has the same triggers themselves. Many of these children go on to develop typical headache migraine in adolescence or adulthood, which is worth saying in advance rather than presenting as a new problem years later.
Formula, evidence and interpretation

About the Rome IV Criteria for Abdominal Migraine

Seven criteria, all required, over at least six months, with episodes occurring at least twice. Paroxysmal episodes of intense acute periumbilical, midline or diffuse abdominal pain lasting an hour or more, and this should be the most severe and distressing symptom. Episodes separated by weeks to months. Pain incapacitating and interfering with normal activities. A stereotypical pattern in that individual. Pain associated with two or more of anorexia, nausea, vomiting, headache, photophobia or pallor. And other medical conditions excluded after appropriate evaluation. Six months is the longest duration rule in the Rome IV child and adolescent chapter, and a deliberate exception — episodes separated by weeks to months cannot be characterised in a shorter window.

On this page

  • Formula
  • Interpreting the result
  • Inputs
  • What it returns
  • How it is calculated
  • Facts & figures
  • Evidence
  • How it compares
  • Pearls & pitfalls
  • Critical actions
  • Why it exists
  • About the creator
  • Limitations
  • If you are the patient
  • FAQ
  • Related calculators
  • References

Formula

Abdominal migraine = ≥ 6 months, episodes occurring ≥ 2 times AND paroxysmal intense periumbilical/midline/diffuse pain ≥ 1 hour, and the most severe and distressing symptom AND episodes separated by weeks to months AND pain incapacitating, interfering with normal activities AND stereotypical pattern and symptoms in that individual AND ≥ 2 of: anorexia | nausea | vomiting | headache | photophobia | pallor AND another medical condition excluded after appropriate evaluation
Six months
The exception in a chapter that otherwise uses two months. Episodes separated by weeks to months need a longer observation period before a pattern is visible.
Stereotypical
The strongest positive feature, shared with cyclic vomiting syndrome. Variability in character or duration argues against the diagnosis and towards a search for a structural cause.
Pallor
One of the six associated features and the most distinctive. Caregivers describe a child going white or grey during an attack, and it is rarely volunteered unless asked.
  • Rome IV requires the pain to be the most severe and distressing symptom, which distinguishes abdominal migraine from disorders where pain is one feature among several.
  • Periumbilical, midline or diffuse — not localised to a quadrant. Localised pain points elsewhere.
  • The associated features overlap almost entirely with typical migraine, which is the point.
  • Most children have a family history of migraine, and many develop typical headache migraine later.

Interpreting the result

Ask about family history of migraine, which is present in most children and often makes the diagnosis land with the family immediately. Identify triggers, which overlap with headache migraine and are frequently modifiable — sleep deprivation, fasting, travel, excitement and stress are the usual ones, and a trigger diary is more useful here than in most functional disorders because the episodes are discrete enough to correlate. Treat individual attacks as you would a migraine, with early intervention, a quiet dark environment, antiemetics and analgesia; and consider prophylaxis where episodes are frequent or disabling enough to justify it. Explain that many children go on to develop typical headache migraine, which prevents that transition being experienced as a new and unexplained illness later. Where criteria are not met, the failing criterion directs you. Episodes shorter than an hour, or occurring more often than every few weeks, do not fit — reconsider functional dyspepsia, IBS or functional abdominal pain NOS. And recurrent severe abdominal pain with vomiting always warrants a thought about intermittent obstruction, particularly malrotation with volvulus, and about urinary tract obstruction, both of which can produce strikingly stereotypical episodes with complete recovery in between.

ScoreBandWhat it meansAction
Criteria metAbdominal migraineStereotypical incapacitating episodes lasting an hour or more with two or more migraine featuresTrigger identification; migraine-style abortive treatment; prophylaxis if frequent or disabling
Criteria not met — episodes too short or too frequentPattern does not fitEpisodes under an hour, or occurring more often than every few weeksConsider functional dyspepsia, IBS or functional abdominal pain NOS
Criteria not met — fewer than two associated featuresInsufficient associated featuresPain fits the pattern but lacks two of anorexia, nausea, vomiting, headache, photophobia or pallorAsk specifically about pallor and photophobia, which are under-reported; reassess after a symptom diary
Criteria not met — episodes not stereotypicalRed flagEpisodes differ in character, site or durationConsider intermittent obstruction, malrotation with volvulus, urinary tract obstruction and metabolic disease

What the Abdominal Migraine needs (7 inputs)

Criteria fulfilled for at least 6 months, with episodes occurring at least twice
Six months is the longest window in the Rome IV child and adolescent chapter, and the only one not shortened to two months. With attacks separated by weeks to months, a shorter window cannot capture the pattern.
Paroxysmal episodes of intense acute periumbilical, midline or diffuse abdominal pain lasting 1 hour or more, and the most severe and distressing symptom
One hour is the minimum. Rome IV also requires the pain to dominate — a child with several equally troublesome symptoms does not meet this criterion.
Episodes separated by weeks to months
Long symptom-free intervals. Daily or weekly pain is a different disorder entirely.
The pain is incapacitating and interferes with normal activities
The child stops what they are doing. Pain that can be worked through does not meet this criterion.
Stereotypical pattern and symptoms in the individual patient
The same episode every time. Families can usually describe it precisely, and that precision supports the diagnosis.
Pain associated with two or more of: anorexia, nausea, vomiting, headache, photophobia, pallor
Two of six. Pallor is the feature caregivers describe most strikingly and that is asked about least often.
After appropriate evaluation, the symptoms cannot be fully explained by another medical condition
Recurrent severe abdominal pain with vomiting also warrants consideration of intermittent obstruction and urinary tract obstruction.

What it returns

Criteria met or not met
All seven criteria are required.
Which criteria are outstanding
Reported when criteria are not met — most commonly the duration rule or the count of associated features.

How it is calculated

Abdominal migraine belongs to the family of paroxysmal disorders that includes migraine and cyclic vomiting syndrome, and shares their architecture rather than their site. The episodes are discrete, self-limiting, stereotypical, and separated by complete wellness — the same temporal shape as a migraine attack, with abdominal pain occupying the position that headache would ordinarily hold. The associated features are the giveaway: anorexia, nausea, vomiting, headache, photophobia and pallor are the accompaniments of migraine, and their presence around an abdominal pain episode is what places it in this family. Mechanistically the picture is incomplete, with the same candidates implicated as in migraine — cortical and brainstem excitability, trigeminovascular activation, and autonomic involvement producing the pallor and gastrointestinal features. Rome IV sensibly declines to adjudicate and defines the disorder by its pattern. That pattern is also why the diagnosis cannot be made from one attack: a single episode of severe abdominal pain with vomiting has a long differential, and only the repetition, the stereotypy and the intervening wellness make it recognisable.

Facts & figures

The paroxysmal disorders of childhood, side by side
FeatureAbdominal migraineCyclic vomitingFunctional dyspepsia
Dominant symptomAbdominal painVomiting and nauseaUpper abdominal discomfort
Episode duration≥ 1 hourHours to daysNot episodic in this sense
Interval between episodesWeeks to monthsWeeks to months≥ 4 times a month
StereotypicalRequiredRequiredNot required
Duration rule6 months2 episodes within 6 months2 months
Migraine family historyUsually presentUsually presentNot characteristic
ProphylaxisMigraine agentsMigraine agentsNot applicable

Abdominal migraine and cyclic vomiting are the same kind of disorder differing in which symptom dominates, and children can move between the two phenotypes over time.

Evidence

Derivation — Rome Foundation, child/adolescent committee

2016

Consensus criteria from the Rome IV committee on childhood functional gastrointestinal disorders in the child and adolescent age band, published in Gastroenterology in 2016.

Consensus-derived. The distinctive structural choice was to retain a six-month duration rule where the rest of the chapter uses two months, because episodes separated by weeks to months cannot be characterised in a shorter window.

Related consensus — NASPGHAN 2008

2008

NASPGHAN consensus statement on cyclic vomiting syndrome, which covers the overlapping paroxysmal disorders and their shared management.

Sets out the trigger identification, abortive treatment and prophylaxis framework that abdominal migraine management follows, given the substantial overlap between the two disorders.

How it compares

Abdominal Migraine vs Paediatric cyclic vomiting syndrome

The same disorder family separated by which symptom dominates — pain or vomiting.

Both are stereotypical, paroxysmal, separated by weeks to months with complete recovery in between, both carry a strong migraine family history, and both are managed with migraine triggers, abortive treatment and prophylaxis. Rome IV separates them by the dominant symptom: abdominal migraine requires pain lasting an hour or more that is the most severe and distressing feature, while cyclic vomiting is defined by the vomiting. Children can shift between the two phenotypes over time, so the distinction matters less for prognosis than for how an acute attack is managed.

Open the Paediatric cyclic vomiting syndrome calculator →

Abdominal Migraine vs Paediatric functional dyspepsia

Episodic and incapacitating with long well intervals, versus frequent and grumbling.

Functional dyspepsia requires symptoms at least four times a month over two months, with no requirement for episodes to be discrete, incapacitating or stereotypical. Abdominal migraine requires attacks separated by weeks to months that stop the child doing anything. A family describing 'attacks' rather than 'pain' — with a clear beginning, a clear end and normality in between — is usually describing abdominal migraine, and the treatment implications differ completely.

Open the Paediatric functional dyspepsia calculator →

Abdominal Migraine vs Functional abdominal pain — not otherwise specified

The residual category that can only be used once abdominal migraine has been considered and excluded.

Functional abdominal pain NOS explicitly requires insufficient criteria for IBS, functional dyspepsia and abdominal migraine. Abdominal migraine therefore has to be actively considered before the residual label is applied, and the most common reason it is missed is that nobody asked about the associated features — a child with periodic severe pain and pallor who was never asked about pallor ends up in the residual category by default.

Open the Functional abdominal pain — not otherwise specified calculator →Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Childhood Functional Gastrointestinal Disorders: Child/Adolescent. Gastroenterology. 2016;150(6):1456-1468.

Pearls & pitfalls

  • Ask about pallor. It is one of the six associated features, families describe it vividly, and it is almost never asked about.
  • Ask about family history of migraine — it is present in most children and often makes the diagnosis obvious to the parent.
  • Six months, not two. This is the one duration exception in the child and adolescent chapter.
  • Complete wellness between attacks is essential; grumbling pain in between points elsewhere.
  • The pain must be the most severe and distressing symptom, not one feature among several.
  • Periumbilical, midline or diffuse — pain localised to a quadrant argues against the diagnosis.
  • Non-stereotypical episodes are a red flag for intermittent obstruction, malrotation with volvulus and urinary tract obstruction.
  • Episodes shorter than an hour do not meet criteria however severe they are.
  • Many children develop typical headache migraine later; saying so in advance prevents it being experienced as a new illness.
  • A trigger diary is more useful here than in most functional disorders, because the episodes are discrete enough to correlate.

Critical actions

  • Take a detailed history of at least two episodes, establishing whether they were identical in onset, site, duration and associated symptoms.
  • Ask specifically about each of the six associated features, including photophobia and pallor.
  • Confirm complete wellness between episodes.
  • Take a family history of migraine.
  • Exclude intermittent obstruction, malrotation with volvulus and urinary tract obstruction where episodes involve vomiting or are not fully stereotypical.
  • Consider metabolic causes where episodes are triggered by fasting or intercurrent illness.
  • Start a trigger diary covering sleep, meals, travel and stress.
  • Provide a plan for treating individual attacks early, as for migraine.
  • Consider prophylaxis where episodes are frequent or disabling, and review it at intervals.

Why this score exists

Keeping the six-month rule in a chapter that shortened everything else to two months is the most revealing decision in these criteria. The paediatric committee's general principle was that long qualifying periods harm children — a child missing school should not have to accumulate half a year of symptoms before anyone will name the problem. They applied that principle everywhere except here, and the exception is not inconsistency. Abdominal migraine is defined by episodes separated by weeks to months, which means a two-month window might contain one attack, or two, and could not possibly establish whether they were stereotypical. Shortening the rule would have made the criteria unusable rather than more accessible. It is a useful reminder that duration thresholds in diagnostic criteria are doing different jobs in different disorders: sometimes they filter out transient illness, and sometimes, as here, they are simply the minimum time required for the pattern that defines the disease to become visible at all.

About the creator

  • Jeffrey S. Hyams

    First author, Rome IV child/adolescent functional gastrointestinal disorders committee

    Chaired the committee that produced the child and adolescent criteria, including H2c.

  • Miguel Saps

    Co-author; paediatric functional gastrointestinal disorders

    Contributed epidemiological work on the paediatric abdominal pain disorders.

  • Carlo Di Lorenzo

    Co-author; paediatric neurogastroenterology and motility

    Co-authored the child and adolescent chapter of Rome IV.

Limitations

  • Consensus criteria with no validation cohort and no measured discrimination against organic causes of episodic pain.
  • Requires a retrospective account of at least two episodes over six months, which delays diagnosis substantially.
  • 'Stereotypical' and 'incapacitating' are judged rather than defined, and depend heavily on the quality of the history.
  • The one-hour minimum is a convention, and families rarely time attacks precisely.
  • The six-month rule means a child with two typical attacks in three months cannot yet be diagnosed, however characteristic they are.
  • The associated features are under-reported unless asked about individually, so the two-of-six threshold is sensitive to how the history is taken.
  • The criteria give no guidance on when imaging is required to exclude intermittent obstruction.
  • No severity or frequency grading, so nothing in the criteria indicates when prophylaxis is warranted.

If you are the patient

Abdominal migraine is migraine that affects the tummy rather than the head. Children get attacks of severe pain around the belly button lasting an hour or more — often much longer — which stop them doing anything at all, and then they are completely well again for weeks or months until the next one. The attacks tend to be almost identical each time, and most families can describe them in detail. Alongside the pain there are usually migraine-type features: going off food, feeling or being sick, a headache, dislike of bright light, and very often going noticeably pale or grey. That pallor is worth mentioning to the doctor, because it is a useful clue and it is one people rarely think to report. Most children with this have a parent or close relative who gets migraines, and quite a few go on to develop ordinary migraine headaches as they get older — that is expected rather than a sign of anything new going wrong. Because it is a migraine, it responds to migraine approaches. The same triggers apply: not enough sleep, irregular sleep, missing meals, long journeys, excitement and stress. Keeping a simple diary of what preceded each attack is genuinely useful here, because the attacks are far enough apart to spot patterns. Attacks are treated early, in a quiet dark room, with medicine for pain and sickness. If they are happening often enough to interfere with school and family life, there are preventive medicines — the same ones used for migraine headaches — that can reduce how often they come.

Frequently asked questions

What are the Rome IV criteria for abdominal migraine?#

Over at least six months and occurring at least twice: paroxysmal episodes of intense periumbilical, midline or diffuse abdominal pain lasting an hour or more and being the most severe and distressing symptom; episodes separated by weeks to months; pain incapacitating and interfering with normal activities; a stereotypical pattern; two or more of anorexia, nausea, vomiting, headache, photophobia or pallor; and exclusion of other conditions.

Why is the duration rule six months when the rest of the chapter uses two?#

Because the disorder is defined by episodes separated by weeks to months. A two-month window might contain a single attack and could not establish whether attacks were stereotypical. Shortening the rule would have made the criteria unusable rather than more accessible, so the committee kept the exception.

Is abdominal migraine actually migraine?#

It behaves as one. The temporal architecture is identical, the associated features are migraine's features, most affected children have a family history of migraine, many develop typical headache migraine later, and the same triggers and the same prophylactic agents apply. Rome IV classifies it as a functional gastrointestinal disorder, but clinically it belongs to the migraine family.

What is the most under-asked diagnostic feature?#

Pallor. Caregivers describe a child going white or grey during an attack in vivid terms once prompted, but rarely volunteer it, because it does not seem like a gastrointestinal symptom. Photophobia is similarly under-reported. Since two of the six associated features are required, how the history is taken determines whether the criteria are met.

What distinguishes it from cyclic vomiting syndrome?#

Which symptom dominates. Abdominal migraine requires pain lasting an hour or more that is the most severe and distressing feature; cyclic vomiting is defined by the vomiting. Everything else — stereotypy, long well intervals, migraine family history, triggers and treatment — is shared, and children can move between the two phenotypes over time.

What red flags argue against the diagnosis?#

Episodes that are not stereotypical, pain localised to one quadrant rather than periumbilical or diffuse, failure to return to normal between attacks, bilious vomiting, and episodes reliably triggered by fasting or intercurrent illness. These raise intermittent obstruction — particularly malrotation with volvulus — urinary tract obstruction, and metabolic disease, all of which can produce strikingly episodic pain.

How is it treated?#

As migraine. Identify and modify triggers, which overlap with headache migraine and are often modifiable — irregular sleep and missed meals are the commonest. Treat individual attacks early with a quiet dark environment, analgesia and antiemetics. Where attacks are frequent or disabling enough to interfere with school and family life, migraine prophylaxis is appropriate.

Will my child grow out of it?#

The abdominal attacks usually become less frequent through adolescence. However, a substantial proportion of children go on to develop typical headache migraine, so it is more accurate to say the presentation changes than that it disappears. Saying this in advance is worthwhile, because it stops the later headaches being experienced as a new and unexplained illness.

Related calculators

  • Paediatric Cyclic Vomiting Syndrome — Rome IV — both age bands, with different criteria for each
  • Paediatric Functional Dyspepsia — Rome IV — four times a month, with PDS and EPS subtyping
  • Functional Abdominal Pain — NOS — Rome IV — the residual category, reached after the other three
  • Paediatric Irritable Bowel Syndrome — Rome IV — plus the constipation clause clinicians miss
  • Cyclic Vomiting Syndrome — Rome IV — stereotypical episodic vomiting

References

Original / primary reference

  1. Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Childhood Functional Gastrointestinal Disorders: Child/Adolescent. Gastroenterology. 2016;150(6):1456-1468 (Rome IV).

Related clinical guidance

  1. Li BUK, Lefevre F, Chelimsky GG, Boles RG, Nelson SP, Lewis DW, et al. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Consensus Statement on the Diagnosis and Management of Cyclic Vomiting Syndrome. J Pediatr Gastroenterol Nutr. 2008;47(3):379-393.

Last updated August 1, 2026. Clinical knowledge base written and curated by GastroAGI Team from primary medical literature.

Written from primary literature and not yet independently clinically reviewed.

For use by qualified healthcare professionals. This calculator supports clinical judgement and does not replace it.