Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction Ozanimod is an oral sphingosine-1-phosphate (S1P) receptor modulator approved for moderate-to-severe ulcerative colitis (UC), with efficacy established in the phase 3 True North program. However, real-world evidence...
Introduction: Acute severe ulcerative colitis (ASUC) is still commonly diagnosed using the 1955 Truelove and Witts criteria. However, these criteria were developed long before corticosteroids, biologics, and small-molecule...
Introduction: Surgery is frequently required during the course of Crohn’s disease (CD), but the optimal extent of mesenteric resection remains controversial. Traditionally, Crohn’s surgery has emphasised bowel preservation...
Introduction: IBD is increasingly recognised as a systemic inflammatory disease, while obesity and metabolic syndrome are becoming progressively more common in the same population. This large real-world study...
Introduction: Risankizumab, an IL-23 p19 inhibitor, is established for moderately to severely active Crohn’s disease based on phase III trials. ARISE-CD examined how well it performs in routine...
Introduction: Despite an expanding range of advanced therapies for inflammatory bowel disease (IBD), many patients fail to achieve durable remission or lose response over time. TL1A is an...
Introduction: Inflammatory bowel disease (IBD), historically concentrated in Western countries, is rapidly becoming a major healthcare challenge across East and Southeast Asia. This review examines a century of...
Acute severe ulcerative colitis (ASUC) in children requires rapid identification of intravenous corticosteroid failure to avoid delayed rescue therapy and colectomy. Intestinal ultrasound (IUS) offers a noninvasive, repeatable...
Introduction: Endoscopic assessment remains the standard for detecting postoperative recurrence after ileocolic resection in Crohn's disease, but it is invasive and resource-intensive. This international multidisciplinary RAND/UCLA consensus developed...
Introduction: Patients with inflammatory bowel disease (IBD) frequently ask whether diet influences disease relapse, yet high-quality prospective evidence has been scarce. The multicenter PREdiCCt study evaluated the impact...
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