Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction: Antibiotic exposure is the best-established risk factor for Clostridioides difficile infection (CDI). However, the contribution of many commonly prescribed non-antibiotic medications has remained uncertain. This large Swedish...
Dyssynergic defecation is commonly evaluated using anorectal manometry, traditionally performed in the left lateral decubitus position. However, defecation normally occurs in the seated position, raising questions about whether...
Somatostatin receptor (SSTR) imaging with ⁶⁸Ga-DOTATATE PET is a cornerstone for well-differentiated neuroendocrine tumors, but its role in poorly differentiated neuroendocrine carcinoma (NEC) has remained uncertain. Previous retrospective...
Introduction: The gut microbiome plays a central role in colorectal cancer (CRC) development, influencing inflammation, metabolism, immune responses, and tumor behavior. While several microbial species have been implicated...
Retatrutide is a once-weekly injectable triple hormone receptor agonist targeting GIP, GLP-1, and glucagon receptors. TRANSCEND-T2D-1 evaluated retatrutide as monotherapy in adults with type 2 diabetes inadequately controlled...
Introduction Immune Checkpoint Inhibitors have transformed cancer treatment across multiple malignancies, but immune-related adverse events remain major limitations to durable therapy. Among these toxicities, Immune Checkpoint Inhibitor Colitis...
Introduction Endometriosis is a chronic inflammatory gynecological disease characterized by ectopic implantation of endometrial tissue and associated with pelvic pain, infertility and impaired quality of life. Although immune...
Introduction Lynch Syndrome remains the most common inherited colorectal cancer predisposition syndrome and is associated with markedly elevated lifetime risk of Colorectal Cancer. High-quality colonoscopic surveillance is central...
Introduction Emerging evidence suggests that the gut microbiome may play a central regulatory role in male reproductive physiology through a proposed “gut–testis axis.” This concept integrates microbial metabolism,...
Introduction The intestinal microbiome has emerged as a major regulator of metabolic health, inflammation and healthy aging. Dietary patterns strongly influence microbial diversity and metabolite production, with fiber-rich...
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