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Trending Topics in Gastroenterology

Explore current gastroenterology questions, clinical answers, and emerging research by topic.

21

Rethinking Antibiotic Strategy in Infected Necrotizing Pancreatitis | Journal of Antimicrobial Chemotherapy

Introduction Infected necrotizing pancreatitis remains one of the most severe complications of acute pancreatitis and is associated with substantial morbidity, organ failure and mortality. Management relies on timely...

22

GCAL Score Helps Triage EUS in Unexplained Bile Duct Dilatation | Indian Journal of Gastroenterology

Introduction Unexplained common bile duct (CBD) dilatation is a frequent and often challenging clinical finding in gastroenterology practice. Although cross-sectional imaging may fail to identify a cause, endoscopic...

23

SPINK1 p.Asn34Ser: Gastroenterology | May 2026

Introduction The SPINK1 gene encodes the pancreatic secretory trypsin inhibitor, a key protective molecule that prevents premature trypsin activation within the pancreas. Dysfunction of this pathway is central...

24

Rome V Gallbladder and Sphincter of Oddi Disorders: Gastroenterology | May 2026

The Rome V Gallbladder and Sphincter of Oddi Disorders chapter substantially modernizes this field by moving away from historically overused functional labels and procedure-driven diagnosis toward a more...

25

Optimal Timing of Endoscopic Necrosectomy After Catheter Drainage: Gastroenterology/ May 2026

Introduction Management of necrotising pancreatitis has evolved toward a minimally invasive, step-up approach, where initial catheter drainage—either percutaneous or endoscopic—is followed by endoscopic necrosectomy only when required. A...

26

Chronic Pancreatitis- From Inflammation to Fibrosis: Gastroenterology | May 2026

Article Type: Review — Basic and Clinical Gastroenterology & Hepatology Introduction and Summary Chronic pancreatitis is a progressive fibro-inflammatory disease characterised by recurrent or persistent abdominal pain, exocrine...

27

SPINK1 p.Asn34Ser: Gastroenterology | May 2026

Introduction The SPINK1 gene encodes the pancreatic secretory trypsin inhibitor, a key protective molecule that prevents premature trypsin activation within the pancreas. Dysfunction of this pathway is central...

28

Gallbladder Polyps: Are We Still Over-Operating Despite New Guidelines? UEG Journal | July 2026

Introduction Gallbladder polyps are commonly detected incidentally, with a prevalence of up to 7% in adults. The vast majority are benign, while only a small fraction represent adenomas...

29

IPMN Surgery vs Surveillance: Annals of Surgical Oncology | April 2026

Introduction Intraductal papillary mucinous neoplasm presents a common yet challenging clinical dilemma—whether to operate or observe. The core issue is diagnostic uncertainty, as current imaging and clinical tools...

30

SMV Involvement in Pancreatic Cancer: Annals of Surgical Oncology | April 2026

Introduction Pancreatic ductal adenocarcinoma is a highly aggressive malignancy frequently involving adjacent vascular structures such as the superior mesenteric vein (SMV). Advances in surgical techniques now allow venous...

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