Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction: Combination therapy with anti–tumor necrosis factor (anti-TNF) agents and thiopurines improves treatment efficacy in inflammatory bowel disease (IBD), but long-term thiopurine use raises concerns regarding infection and...
Introduction: Ulcerative colitis (UC) is a chronic inflammatory disease characterized by relapsing and remitting colonic inflammation. The updated 2025 American College of Gastroenterology (ACG) Guideline emphasizes treat-to-target management,...
Introduction: The relationship between alcohol consumption and inflammatory bowel disease (IBD) has remained controversial. This large prospective study demonstrates that the effect of alcohol depends on an individual's...
Introduction: Endoscopy remains the gold standard for assessing inflammatory bowel disease (IBD) activity but is invasive, costly, and resource-intensive. This real-world study evaluated whether integrating intestinal ultrasound (IUS)...
Introduction: Diet plays an important role in the development of Crohn's disease (CD), but the effects of specific dietary fiber subtypes remain unclear. This prospective study evaluated whether...
Introduction: Clinical trials in inflammatory bowel disease (IBD) are becoming increasingly expensive, complex, and difficult to conduct. This review explores the emerging role of digital twins—virtual, data-driven replicas...
Introduction: Janus kinase (JAK) inhibitors have transformed the treatment of moderate-to-severe ulcerative colitis (UC), particularly in patients who have failed biologic therapies. However, direct comparisons between upadacitinib (UPA)...
Introduction: The global incidence of inflammatory bowel disease (IBD) continues to rise, particularly in newly industrialized countries. This comprehensive systematic review evaluated how race, ethnicity, geography, and migration...
Introduction: Acute severe ulcerative colitis (ASUC) remains one of the most life-threatening emergencies in inflammatory bowel disease. Despite advances in IBD therapy, first-line management has changed little over...
Introduction: Ulcerative colitis (UC) is a chronic inflammatory bowel disease with a rising global burden. Although current therapies are effective, many patients fail treatment or experience adverse effects....
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