Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction Helicobacter pylori infection remains an important paediatric gastrointestinal infection worldwide, yet its diagnosis and treatment in children differ substantially from adult practice. The joint ESPGHAN–NASPGHAN guidelines advocate...
Introduction Tranexamic acid has been widely used across trauma, surgical and hemorrhagic settings because of its antifibrinolytic effects and ability to stabilize clot formation. Earlier small studies suggested...
Introduction Eosinophilic oesophagitis is an increasingly recognized type 2 inflammatory disorder characterized by oesophageal eosinophilia, dysphagia and food-related symptoms. Although EoE occurs across all age groups, differences in...
Introduction Eosinophilic oesophagitis (EoE) is a chronic Th2-mediated inflammatory disease characterized by epithelial barrier dysfunction, basal cell hyperplasia and persistent mucosal remodeling. Even after inflammatory control, epithelial transcriptomic...
Introduction Exclusive enteral nutrition (EEN) is a well-established induction therapy in pediatric Crohn’s disease, where it offers anti-inflammatory efficacy while avoiding corticosteroid-related toxicity. In adults, however, EEN has...
The Rome V Gastroduodenal Disorders chapter introduces several important conceptual, diagnostic, and therapeutic refinements across functional dyspepsia (FD), nausea/vomiting disorders, belching disorders, inability to belch syndrome, and rumination...
Rome V substantially expands pediatric upper gastrointestinal disorders of gut–brain interaction (DGBI), moving beyond the narrower Rome IV framework to include pediatric esophageal pain disorders, esophageal air-transit disorders,...
Rome V reframes functional esophageal disorders as esophageal disorders of gut–brain interaction (E-DGBI), emphasizing that these syndromes arise from altered esophageal sensory signaling and central perceptual processing rather...
Introduction Achalasia is a chronic oesophagal motility disorder characterised by impaired lower oesophagal sphincter relaxation and food stasis. Long-standing stasis, bacterial overgrowth, and chronic inflammation have raised concerns...
Introduction Gastric polyps are frequently encountered during upper gastrointestinal endoscopy and represent a heterogeneous group of lesions ranging from benign fundic gland polyps to premalignant adenomas and neuroendocrine...
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