Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction Frailty and reduced functional capacity are increasingly recognized as major prognostic determinants in patients with Cirrhosis awaiting Liver Transplantation. The Six-Minute Walk Test is widely used to...
Introduction Wilson disease (WD) is an autosomal recessive copper metabolism disorder caused by pathogenic variants in the ATP7B gene. Although genetic confirmation is increasingly incorporated into diagnostic algorithms,...
Introduction Autoimmune hepatitis (AIH) in children is typically managed with corticosteroids and azathioprine, achieving remission in most patients. However, a subset of paediatric patients remain refractory to standard...
Introduction The concept of recompensated cirrhosis has gained increasing importance with the advent of effective disease-modifying therapies for chronic liver disease, including antiviral treatment and sustained alcohol abstinence....
Introduction Cirrhosis and hepatocellular carcinoma (HCC) represent closely interconnected consequences of chronic liver disease, with portal hypertension serving as a central driver of hepatic decompensation and a major...
Introduction Alcohol use disorder (AUD) remains a major global health challenge with limited pharmacologic treatment options and persistently high relapse rates. Although behavioural therapies remain foundational, currently approved...
Introduction Primary biliary cholangitis is a chronic cholestatic liver disease that can progress to cirrhosis and liver failure if inadequately treated. While ursodeoxycholic acid remains the first-line therapy,...
Surgery in patients with cirrhosis is no longer viewed as uniformly prohibited, but it remains high-risk and must be approached in a structured way. The two most important...
Introduction Minimal hepatic encephalopathy (MHE) and physical frailty are highly prevalent yet often under-recognised complications in patients with advanced chronic liver disease (AdvCLD). While MHE reflects subtle neurocognitive...
Introduction: Cirrhosis is increasingly recognised as a multisystem disease influenced by inflammation, microbiome alterations, and extrahepatic factors. Poor oral health, particularly periodontitis, contributes to systemic inflammation and bacterial...
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