Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction: Noninvasive tests (NITs) have become central to the diagnosis and staging of metabolic dysfunction–associated steatotic liver disease (MASLD), reducing reliance on liver biopsy. However, most validation studies...
Introduction: Identifying patients with at-risk metabolic dysfunction–associated steatohepatitis (MASH) is essential because they carry a substantially higher risk of cirrhosis, hepatocellular carcinoma, and liver-related mortality. Although liver biopsy...
Introduction: The transition from non alcoholic fatty liver disease (NAFLD) to the steatotic liver disease (SLD) nomenclature has redefined metabolic dysfunction–associated steatotic liver disease (MASLD) as the principal...
Introduction: Accurate prediction of liver-related events (LREs) is essential for risk stratification and therapeutic decision-making in metabolic dysfunction–associated steatotic liver disease (MASLD). Although liver biopsy remains the reference...
Introduction: Obesity, insulin resistance, and metabolic dysfunction-associated steatotic liver disease (MASLD) are closely linked metabolic disorders with limited disease-modifying therapies. This study identifies CD59, traditionally known as a...
Introduction: The treatment of obesity has entered a new era with several highly effective pharmacological agents. This large systematic review and network meta-analysis compared the efficacy, safety, cardiovascular...
Introduction: Cardiovascular–Kidney–Metabolic (CKM) syndrome recognizes the interconnected relationship between obesity, type 2 diabetes, chronic kidney disease (CKD), and cardiovascular disease (CVD). These first multidisciplinary guidelines from the AHA,...
Introduction: Metabolic dysfunction–associated steatotic liver disease (MASLD), obesity, and type 2 diabetes (T2D) represent interconnected global epidemics that frequently coexist and amplify one another. Together, they accelerate liver...
Introduction: Chronic hepatitis B (CHB), hepatic steatosis, and type 2 diabetes mellitus (T2DM) frequently coexist, creating a growing clinical challenge. This multinational study evaluated whether T2DM independently influences...
Introduction: Metabolic dysfunction-associated steatohepatitis (MASH) remains a leading cause of cirrhosis, liver failure, and hepatocellular carcinoma, with limited treatment options. This study evaluated DT-109, a novel glycine-based tripeptide,...
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