Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction Metabolic dysfunction-associated steatotic liver disease is now recognized as a multisystem metabolic disorder affecting not only the liver but also cardiovascular, renal, and endocrine systems. Parallel to...
Introduction With the rapid rise of obesity and type 2 diabetes, incretin-based therapies such as Tirzepatide have transformed metabolic care. These agents offer substantial benefits in weight reduction...
Introduction Autoimmune pancreatitis (AIP) is a unique IgG4-related inflammatory disease with generally favourable outcomes following glucocorticoid therapy. However, beyond pancreatic inflammation, extension into the peripancreatic vasculature can occur,...
Introduction: Metastatic pancreatic cancer continues to carry a dismal prognosis, with limited effective options after failure of first-line gemcitabine-based therapy. Liposomal irinotecan (nal-IRI) combined with 5-fluorouracil/leucovorin (5-FU/LV) is...
Introduction Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary liver cancer and carries a poor prognosis even after curative surgery. Recurrence rates exceed 50%, particularly in patients...
Introduction Cholangiocarcinoma (CCA) is the second most common primary liver cancer and is associated with poor prognosis due to late diagnosis and aggressive tumour biology. Increasing evidence links...
Introduction Acute pancreatitis (AP) is often considered a self-limited illness once the acute episode resolves, with survival exceeding 95%. However, increasing evidence suggests that AP frequently initiates a...
This large population-based cohort study evaluated the relationship between metabolic syndrome (MetS) and the risk of cholangiocarcinoma (CCA), including both intrahepatic and extrahepatic subtypes. The study included nearly...
Introduction Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers, largely because it is usually diagnosed late. Individuals with familial risk, pathogenic germline variants, or pancreatic cystic...
Overview The neutrophil-to-lymphocyte ratio (NLR) is a simple, cost-effective biomarker derived from routine blood tests. It measures the ratio of neutrophils (a type of white blood cell involved...
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