Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction Liver transplantation has dramatically improved survival in patients with end-stage liver disease and hepatocellular carcinoma. However, long-term outcomes are often compromised by complications such as graft rejection,...
Introduction Donation after circulatory death (DCD) has emerged as an important strategy to expand the donor pool in liver transplantation. However, compared to brain-dead donors, DCD grafts are...
Introduction Extensive porto-mesenteric thrombosis has traditionally been considered one of the most difficult situations in liver transplantation because adequate portal inflow is essential for graft regeneration and long-term...
Introduction Early allograft dysfunction (EAD) remains a major challenge after living donor liver transplantation (LDLT), often driven by portal hyperperfusion and small-for-size graft physiology. Splenectomy has been used...
Introduction Neuroprotection remains a central challenge in the management of acute liver failure, where cerebral oedema and intracranial hypertension are major drivers of mortality. Traditionally, invasive intracranial pressure...
Introduction Primary sclerosing cholangitis is a unique indication for liver transplantation because long-term outcomes are influenced not only by graft survival, but also by the risks of acute...
This large single-centre analysis evaluated whether earlier liver transplantation improves survival in patients with perihilar cholangiocarcinoma (pCCA) treated with standardised neoadjuvant therapy and transplant protocol. The key question:...
Multiple bile ducts (MBDs) in living donor liver transplantation (LDLT) remain a major technical challenge, particularly in right lobe grafts. This large retrospective study analysed 1,780 microsurgical biliary...
Frailty is a powerful predictor of outcomes after liver transplantation, but it cannot be used alone to determine transplant candidacy because many frail patients still achieve acceptable survival....
The Gut–Liver–Muscle Axis: Overview and Key Insights The "gut-liver-muscle axis" is an emerging concept that highlights the interconnected relationship between gut microbiota, liver metabolism, and skeletal muscle health....
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