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Trending Topics in Gastroenterology

Explore current gastroenterology questions, clinical answers, and emerging research by topic.

31

Gastrointestinal Involvement in Scleroderma: Gastroenterology | May 2026

Summary Systemic sclerosis (SSc), the systemic form of scleroderma, is a multisystem disorder characterised by fibrosis, vasculopathy, and immune dysregulation. Gastrointestinal involvement is extremely common, affecting up to...

32

Antibiotic-Associated Diarrhea in ICU: JGH | March 2026

Introduction Antibiotic-associated diarrhea (AAD) is a frequent and clinically significant complication of antimicrobial therapy, particularly in critically ill patients. The pathogenesis primarily involves disruption of the gut microbiota,...

33

Probiotics in IBS: JGH | March 2026

Introduction Irritable bowel syndrome is a highly prevalent functional gastrointestinal disorder with significant impact on quality of life and healthcare costs. Despite multiple therapeutic options, management remains challenging...

34

Clostridioides difficile Infection: AMJ, March 2026

This review highlights that CDI management now requires both accurate diagnosis and a strategy to prevent recurrence. Diagnosis should not rely on a single test alone, because PCR...

35

IBS Pharmacotherapy Safety: AMJ, March 2026

Introduction Choosing drug therapy for irritable bowel syndrome (IBS) requires balancing symptom benefit against treatment-related adverse effects. While clinicians often use the number needed to treat (NNT) to...

36

Global Dietary Patterns Influence Severity of IBS: CGH, March 2026

The role of habitual diet in the global epidemiology of irritable bowel syndrome (IBS) remains incompletely understood. In this large international analysis from the Rome Foundation Global Epidemiology...

37

Mucus Brushing and SIBO: Frontline Gastroenterology, March 2026

Introduction Upper small intestinal bacterial overgrowth (USIBO) is characterised by excessive bacterial colonisation in the duodenum or proximal jejunum, often leading to symptoms such as bloating, abdominal distension,...

38

Defecography Metrics in Chronic Constipation: Gastroenterology | March 2026

Introduction Chronic constipation is frequently evaluated using physiologic testing such as fluoroscopic defecography and high-resolution anorectal manometry to identify pelvic floor dysfunction and evacuation disorders. A recent study...

39

Colonoscopy is the Best for CRC Screening: Gastroenterology | March 26

Introduction Colonoscopy has become the dominant colorectal cancer (CRC) screening test in the United States, credited with major reductions in CRC incidence and mortality through detection and polypectomy....

40

SAPP Defines “Gut Health”: Nature Reviews Gastro & Hepatol | Feb. 2026

“Gut health” is widely used by clinicians, researchers, industry, and the public—but until now lacked a unified, clinically usable definition. This ISAPP consensus statement convened an interdisciplinary expert...

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