Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction Immune Checkpoint Inhibitors have transformed cancer treatment across multiple malignancies, but immune-related adverse events remain major limitations to durable therapy. Among these toxicities, Immune Checkpoint Inhibitor Colitis...
Introduction Endometriosis is a chronic inflammatory gynecological disease characterized by ectopic implantation of endometrial tissue and associated with pelvic pain, infertility and impaired quality of life. Although immune...
Introduction Lynch Syndrome remains the most common inherited colorectal cancer predisposition syndrome and is associated with markedly elevated lifetime risk of Colorectal Cancer. High-quality colonoscopic surveillance is central...
Introduction Emerging evidence suggests that the gut microbiome may play a central regulatory role in male reproductive physiology through a proposed “gut–testis axis.” This concept integrates microbial metabolism,...
Introduction The intestinal microbiome has emerged as a major regulator of metabolic health, inflammation and healthy aging. Dietary patterns strongly influence microbial diversity and metabolite production, with fiber-rich...
Introduction Healthcare systems are increasingly recognizing the environmental impact of hospital food services, particularly the high carbon footprint associated with meat-heavy diets. At the same time, maintaining adequate...
Introduction Chronic idiopathic constipation (CIC) is one of the most common disorders of gut–brain interaction and is associated with substantial impairment in quality of life, healthcare utilization and...
Introduction Serrated polyposis syndrome (SPS) is now recognized as the most common colorectal polyposis syndrome and an important precursor condition for colorectal cancer (CRC). The syndrome is characterized...
Introduction Modern biologic therapies have significantly improved remission rates in Crohn’s disease (CD), primarily through suppression of mucosal immune activation. However, despite clinical and endoscopic remission, many patients...
Introduction Seronegative enteropathies (SNEs) represent a challenging group of disorders characterised by villous atrophy with negative coeliac serology. They include both seronegative coeliac disease (SNCD) and a broad...
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