Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction: Decompensated cirrhosis has traditionally been considered an irreversible stage of liver disease, associated with poor survival and frequent complications such as ascites, variceal bleeding, and hepatic encephalopathy....
Introduction Management of alcohol use disorder in patients with cirrhosis remains a clinical challenge, where drug safety is as critical as efficacy. Acamprosate is generally preferred due to...
Introduction Portopulmonary hypertension represents a complex cardiopulmonary complication of cirrhosis that significantly impacts prognosis and transplant eligibility. Recent data from the PORTO-DETECT cohort have suggested that even early-stage...
Introduction Endoscopic band ligation (EBL) remains the standard of care for managing esophageal varices, both in acute variceal bleeding and for prophylaxis. However, post-banding ulcer bleeding (PBUB) is...
Introduction Ammonia has long been recognized as a central neurotoxin in the pathogenesis of hepatic encephalopathy, but its clinical use in cirrhosis has remained inconsistent because of major...
Introduction Acute-on-chronic liver failure (ACLF) is a severe syndrome characterized by acute decompensation of cirrhosis, multiorgan failure, and high short-term mortality. The current EASL-CLIF criteria have been widely...
Introduction Ammonia has long been recognised as a central neurotoxin in the pathogenesis of hepatic encephalopathy, but its clinical use in cirrhosis has remained inconsistent because of major...
Introduction Harmful alcohol use remains a major cause of chronic liver disease, cirrhosis, hepatocellular carcinoma (HCC), and liver-related mortality worldwide. Despite advances in hepatology care, effective pharmacologic strategies...
Portopulmonary hypertension (PoPH) is a serious but frequently underdiagnosed complication of cirrhosis and portal hypertension. Traditionally, attention has focused on advanced PoPH, while mild or “borderline” pulmonary hemodynamic...
Introduction Acute-on-chronic liver failure (ACLF) is one of the most lethal syndromes in hepatology, characterized by abrupt hepatic decompensation, intense systemic inflammation, multi-organ failure, and very high short-term...
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