Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Introduction: Metastatic Crohn’s disease (MCD), also referred to as cutaneous or genital Crohn’s disease, is a rare extraintestinal manifestation characterized by granulomatous skin inflammation occurring at sites separate...
Darvadstrocel is an allogeneic adipose-derived mesenchymal stem cell therapy designed to promote fistula healing through anti-inflammatory and immunomodulatory mechanisms. It is administered locally into conditioned fistula tracts after...
Inflammaging and sarcopenia are two interconnected hallmarks of aging that contribute to frailty, disability, metabolic dysfunction, loss of independence, and reduced quality of life. Inflammaging refers to chronic...
Clostridioides difficile infection (CDI) remains one of the most important triggers of disease flares, hospitalization, treatment failure, colectomy, and mortality in patients with inflammatory bowel disease. Every patient...
Introduction: Complex perianal fistulas represent one of the most debilitating manifestations of Crohn’s disease, often causing chronic pain, drainage, recurrent infections, and substantial impairment in quality of life....
This landmark study identifies neutralizing autoantibodies against interleukin-10 (IL-10) as a previously underrecognized mechanism driving inflammatory bowel disease. IL-10 is a critical anti-inflammatory cytokine that maintains intestinal immune...
Histopathology remains a cornerstone for diagnosing pediatric inflammatory bowel disease, but differentiating Crohn’s disease from ulcerative colitis can be challenging, especially in young children. This study evaluated whether...
Introduction: Vitamin D deficiency is highly prevalent among patients with inflammatory bowel disease (IBD) and has been associated with increased disease activity, impaired mucosal healing, reduced quality of...
Introduction: Crohn's Disease–associated complex perianal fistulas remain one of the most difficult complications in inflammatory bowel disease management, causing major morbidity, impaired quality of life, and high rates...
Introduction Crohn's Disease postoperative recurrence remains one of the greatest challenges after intestinal resection, with endoscopic recurrence occurring in the majority of patients within the first year. Despite...
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