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Trending Topics in Gastroenterology

Explore current gastroenterology questions, clinical answers, and emerging research by topic.

61

Vasculobiliary Injury in Laparoscopic and Open Cholecystectomy HPB | 2026

Introduction Vasculobiliary injury is one of the most serious complications associated with cholecystectomy, particularly when a bile duct injury is accompanied by injury to the hepatic artery or...

62

Autologous Fat Injection for Pouch-Related Fistulae: UEG Journal — December 2025

Introduction Ileal pouch–anal anastomosis (IPAA) is the standard restorative surgery for patients with ulcerative colitis (UC) or familial adenomatous polyposis (FAP) after colectomy. Although IPAA significantly improves the...

63

LIR!C Trial: Lancet Gastroenterol Hepatol, 2026

Introduction Management of localised ileocaecal Crohn’s disease traditionally prioritises medical therapy, particularly anti-TNF agents such as infliximab. However, the original LIR!C randomised trial demonstrated that laparoscopic ileocaecal resection...

64

Broad-Spectrum Antibiotic Prophylaxis May Improve Outcomes After Pancreatoduodenectomy: Annals of Surgery, March 2026

Introduction Pancreatoduodenectomy (Whipple procedure) is a complex surgical operation performed for pancreatic and periampullary diseases. Despite advances in surgical techniques and perioperative care, the procedure continues to carry...

65

Metachronous CRC Risk in Lynch Syndrome: Clinical Gastroenterolo and Hepatolo, March 2026

Introduction Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome, caused by germline mutations in DNA mismatch repair genes (MLH1, MSH2, MSH6, PMS2, EPCAM). Individuals...

66

GLP-1 Drugs vs Bariatric Surgery: JAMA Surgery | March 2026

Introduction The introduction of second-generation GLP-1 receptor agonists such as semaglutide and tirzepatide has transformed obesity treatment. These medications produce substantial weight loss and metabolic improvements, approaching outcomes...

67

Early Thrombus Removal in Iliofemoral DVT: Annals of Surgery | February 2026 | DOI: 10.1097/SLA.0000000000006765

Introduction Iliofemoral deep vein thrombosis (IF-DVT) carries a high risk of post-thrombotic syndrome (PTS), a chronic and disabling complication that significantly impairs quality of life. Early thrombus removal...

68

Staging Laparoscopy in Gastric Cancer: Surgical Oncology Feb. 2026

Introduction Radiographically occult peritoneal carcinomatosis (PC) is a well-recognised challenge in gastric and Siewert III gastroesophageal junction adenocarcinoma. Current guidelines recommend staging laparoscopy (SL) before neoadjuvant systemic therapy...

69

ROGER Trial- BJS Feb.26

The ROGER randomised clinical trial compared robotic transabdominal preperitoneal repair (rTAPP) with laparoscopic totally extraperitoneal repair (TEP) for elective primary inguinal hernia. In this single-centre, patient- and investigator-blinded...

70

Delayed Leak Recognition After Colon Resection - JAMA Surgery Feb 26

Anastomotic leak remains a leading driver of morbidity and mortality after colon resection. This large Veterans Affairs Surgical Quality Improvement Program cohort study evaluated whether the timing of...

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