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Trending Topics in Gastroenterology

Explore current gastroenterology questions, clinical answers, and emerging research by topic.

61

Fasting Alone Does Not Stabilize Stomach Volume During Pancreatic SBRT Journal: Practical Radiation Oncology | June 2026

Pancreatic stereotactic body radiotherapy (SBRT) requires highly precise treatment because the pancreas lies immediately adjacent to radiosensitive organs such as the stomach and duodenum. Most centers instruct patients...

62

DOTATATE PET and Poorly Differentiated Extrapulmonary NEC: JNM | June 2026

Somatostatin receptor (SSTR) imaging with ⁶⁸Ga-DOTATATE PET is a cornerstone for well-differentiated neuroendocrine tumours, but its role in poorly differentiated neuroendocrine carcinoma (NEC) has remained uncertain. Previous retrospective...

63

Fasting Alone Does Not Stabilise Stomach Volume During Pancreatic SBRT: Practical Radiation Oncology | June 2026

Pancreatic stereotactic body radiotherapy (SBRT) requires highly precise treatment because the pancreas lies immediately adjacent to radiosensitive organs such as the stomach and duodenum. Most centres instruct patients...

64

Multimodality Therapy Remains Key in Recurrent Rectal Cancer : Cancer | June 2026

Introduction: Locoregionally recurrent rectal cancer (LRRC) remains one of the most challenging scenarios in colorectal oncology. Recurrence within the pelvis is often associated with significant morbidity, impaired quality...

65

Nal-IRI Improves Second-Line Outcomes in Pancreatic Cancer : Pancreatology | June 2026

Introduction: Despite advances in systemic therapy, metastatic and recurrent pancreatic cancer remains associated with poor survival. Following progression on first-line gemcitabine-based chemotherapy, treatment options have historically been limited....

66

Early-Onset Cancers Rising Selectively in Spain : Ann Oncol | June 2026

Introduction: Concerns regarding increasing cancer incidence among adults younger than 50 years have gained global attention over the past decade. Reports from several countries have suggested a rise...

67

B-Cell Dysfunction Drives Immune Escape in iCCA : Gut | June 2026

Introduction: Intrahepatic cholangiocarcinoma (iCCA) is one of the most aggressive primary liver malignancies, characterized by poor survival and limited therapeutic options. Although recent advances in immunotherapy have offered...

68

RTOG 0848: Adjuvant Chemoradiotherapy Fails Overall, but Node-Negative Patients May get benifit: JCO| June 2026

RTOG 0848 is one of the largest randomized phase III trials evaluating the role of adjuvant chemoradiotherapy after curative-intent resection of pancreatic head adenocarcinoma. The study addressed a...

69

Underwater Endoscopy for Colorectal Neoplasia : Frontline Gastroenterol | Jun 2026

Introduction: Water-assisted and immersion-based endoscopic techniques are increasingly transforming the diagnosis and treatment of colorectal neoplasia. Unlike conventional gas insufflation, these approaches replace luminal gas with water or...

70

GLP-1 Agonists with TNT in Rectal Cancer: Metabolic Optimization Meets Oncology: British Journal of Surgery | June 2026

This review explores a novel concept: whether GLP-1 receptor agonists can improve outcomes when combined with total neoadjuvant therapy in locally advanced rectal cancer. Total neoadjuvant therapy is...

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