Trending Topics in Gastroenterology
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
Explore current gastroenterology questions, clinical answers, and emerging research by topic.
This study highlights the importance of comprehensive genomic profiling in pancreatic adenocarcinoma, not only for identifying targetable alterations but also for defining biologically distinct prognostic subgroups. The analysis...
BRAF V600E-mutant metastatic colorectal cancer represents one of the most aggressive molecular subtypes of colorectal cancer, accounting for approximately 8%–12% of cases and historically associated with poor outcomes....
Early age–onset colorectal cancer is increasing globally and is now a major public health concern, especially because many patients present before routine screening age. This population-based Texas Cancer...
PRISM is one of the largest prospective real-world studies evaluating systemic therapy for unresectable hepatocellular carcinoma in routine clinical practice across Japan. This analysis reports outcomes from the...
Introduction: Introduction: Carbohydrate antigen 19-9 (CA19-9) is the most widely used serum biomarker in pancreatic ductal adenocarcinoma (PDAC), guiding treatment response assessment, prognostication, and postoperative surveillance. However, approximately...
Introduction: Ulcerative Colitis is associated with an increased long-term risk of Colitis-Associated Cancer, particularly in patients with prolonged inflammatory disease activity. Although microbiome dysbiosis is increasingly implicated in...
Introduction: Early Rectal Cancer and advanced rectal adenomas are increasingly managed with organ-preserving local excision strategies. Endoscopic Submucosal Dissection and Transanal Endoscopic Microsurgery are the two principal approaches...
Introduction: Gastric Cancer remains a major global cause of cancer mortality, particularly in East Asia, where early detection through upper gastrointestinal endoscopy is central to improving outcomes. Artificial...
Introduction: Colorectal Cancer is increasingly recognized as a disease strongly influenced by host–microbiome metabolic interactions. Although gut microbial dysbiosis has been linked to colorectal carcinogenesis, the mechanistic interplay...
Introduction Gastroesophageal Adenocarcinoma remains an aggressive malignancy with limited long-term survival despite HER2-directed therapy. Since the ToGA era, trastuzumab-based chemotherapy has remained the standard first-line treatment, but therapeutic...
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