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Trending Topics in Gastroenterology

Explore current gastroenterology questions, clinical answers, and emerging research by topic.

81

Enterococcus faecium DNA in acute decompensated cirrhosis

Enterococcus faecium (EF) DNA plays a significant role in acute decompensated liver cirrhosis, particularly in cases of acute-on-chronic liver failure (ACLF). Cirrhosis, a severe liver condition, causes over...

82

Hepatitis B Guidelines- AASLD 2025

The 2025 AASLD/IDSA Practice Guideline on the treatment of chronic hepatitis B was released on November 4, 2025. It includes significant updates compared to the previous guidelines from...

83

Emerging and potential use of CRISPR in human liver disease

CRISPR technology is rapidly emerging as a transformative tool in the study and treatment of human liver diseases. Its versatility and precision have opened up new possibilities for...

84

Mean arterial pressure in patients with cirrhosis and AKI

Mean arterial pressure (MAP) plays a critical role in managing patients with cirrhosis and acute kidney injury (AKI), but its application in this population is nuanced and requires...

85

The synergy of carvedilol and simvastatin

The synergy between carvedilol and simvastatin represents a promising multifaceted approach to managing portal hypertension in patients with cirrhosis, particularly those who exhibit poor responses to traditional non-selective...

86

DILI control compounds list: An analysis of FAERS data

The analysis of the DILI (drug-induced liver injury) control compounds list using FAERS (FDA Adverse Event Reporting System) data aimed to validate the consensus-driven list of DILI-positive and...

87

Nucleos(t)ide analogue cessation and HBV flare

Nucleos(t)ide analogue (NA) cessation in chronic hepatitis B (CHB) infection is a complex process that can lead to hepatitis flares, characterized by a rise in alanine aminotransferase (ALT)...

88

Paediatric acute hepatitis of unknown origin (PAHUO)

Overview: Paediatric Acute Hepatitis of Unknown Origin (PAHUO) refers to cases of acute liver inflammation in children where no known cause—such as viral hepatitis (A, B, C, D,...

89

Sequential therapy with antisense oligonucleotide and immune modulator as HBV cure

Sequential therapy combining antisense oligonucleotides (ASOs) and immune modulators represents a promising strategy to achieve a functional cure for chronic hepatitis B virus (HBV). Below, I will explain...

90

MetALD: Position statement by an expert panel

The expert position statement on Metabolic dysfunction- and Alcohol-related Liver Disease (MetALD) provides a comprehensive overview of the definition, diagnosis, and management of MetALD within the newly updated...

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